No insider purchase over the last 90 days. The latest, by Ashiya Mona, was filed 02 Sept 2025.
Shattuck Labs, Inc. belongs to the Healthcare & Pharma sector. Filings by its managers are published through SEC (Form 4). 6 insiders have disclosed 17 filings since 21 October 2025.
The flow runs one way only: 2 sales worth €171k, from 2 insiders, and no purchase. The largest single trade was a sale of €169k by Pandite Arundathy N., published on 14 May 2026, equal to 0.026% of the market capitalisation.
Compared with its exchange (5,814 companies, median 19 filings), a count of 17 filings is below the norm. Looking back to 2021, when coverage begins, insiders filed 8 purchases and 31 sales. For the fiscal year to 31 December 2025, the annual 10-K puts revenue at 1.0 m USD and net income at -48.8 m USD.
Between a trade and the moment it shows up on SEC (Form 4), the median delay is 2 days. The legal deadline for a Form 4 is two business days after the transaction. A sale on its own says little: insiders also sell to pay tax, fund a purchase or diversify.
Elsewhere in the same sector, our signals recently picked up insider purchases at Cooper Companies, Inc. and Anixa Biosciences Inc. Every figure here comes from the filings published by SEC (Form 4) and describes the past, not future prices; it is not investment advice.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate Shattuck Labs, Inc. Strong Buy (bullish), based on 10 analysts. Average price target: US$15.40.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
FY ended December 2025 · cache
25 of 102 declarations
Shattuck Labs, Inc. (ticker: STTK) is a U.S.-listed biotechnology company traded on NASDAQ in the United States. Founded in 2016, the company is organized around research and development operations in Durham, North Carolina, and a corporate office in Austin, Texas. Its business is centered on the discovery and development of potential therapies for inflammatory and immune-mediated diseases, positioning Shattuck as a clinical-stage biotech rather than a commercial-stage pharmaceutical company. For investors, the key question is not current product revenue, but rather the probability that one or more of its pipeline assets can generate clinically meaningful data and ultimately create licensing or commercial value.
Scientifically, Shattuck Labs has built its strategy around the biology of TNF superfamily receptors, especially the DR3/TL1A signaling axis. The company describes itself as developing next-generation monoclonal and bispecific antibodies designed to modulate these pathways. Its lead program is SL-325, a first-in-class DR3 blocking antibody being advanced in inflammatory disease indications. This focus is important because the company has recently sharpened its pipeline strategy, emphasizing immunology and inflammation after prioritizing programs and discontinuing others. That narrower focus can improve capital efficiency, but it also increases dependence on a small number of clinical assets.
From a competitive standpoint, Shattuck Labs remains a small-cap biotech with meaningful execution risk. It is not a diversified large pharma group and does not have a broad commercial portfolio to cushion setbacks. Its market position is therefore defined by scientific differentiation, clinical milestones, and the ability to extend cash runway. In the highly competitive immunology landscape, the company’s challenge is to generate data strong enough to stand out against larger peers developing therapies for similar inflammatory and autoimmune indications. At the same time, its DR3-focused approach gives it a more focused narrative than many platform biotechs.
Recent developments have been material. In its March 2026 year-end update, Shattuck said SL-325 Phase 1 enrollment was nearing completion, with human data expected in the second quarter of 2026 and a Phase 2 trial in Crohn’s disease expected to start in the third quarter of 2026. The company also disclosed a strengthened balance sheet after recent capital raises and said its current cash resources, together with proceeds from an at-the-market facility and assuming warrant exercise, were expected to fund operations into 2029 under its plans. For international equity investors, STTK is a classic development-stage biotech story: high risk, binary clinical catalysts, and potential upside tied to proof-of-concept execution on NASDAQ in the United States.
Purchases our model currently ranks for the recommendations list.
All recommendations| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 1.0 m USD | -48.8 m USD | -0.70 USD | 10-K |
| Dec 2024 | 5.7 m USD | -75.4 m USD | -1.49 USD | 10-K |
| Dec 2023 | 1.7 m USD | -87.3 m USD | -2.05 USD | 10-K |
| Dec 2022 | 652,000 USD | -101.9 m USD | -2.41 USD | 10-K |
| Dec 2021 | 30.0 m USD | -45.0 m USD | -1.07 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.