Wave Life Sciences Ltd. Stock: price and directors' dealings · United States · SEC (Form 4)Follow the Wave Life Sciences Ltd. stock price and the full insider trade history of the company, a listed issuer based in United States. Shares are listed on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Wave Life Sciences Ltd. has logged 80 public disclosures. Market capitalisation: €1.1bn. The latest transaction was disclosed on 30 March 2026 (Acquisition). Among the most active insiders: BOLNO PAUL. Every trade is free.
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Last declaration on 30 March 2026
All Executives80 Thresholds0 Prospectus0 Other0
Declarations 80 total
▲ Director · Executives · 26 Mar 2026
4,954,558 shares @ US$6.06 47.6% of flow Ordinary Shares SEC:0001231919-26-000297:0
Canonical exit: 24 Jun 2026 (T+90) ● Director · Executives · 23 Mar 2026
3,901,348 shares 0Ordinary Shares SEC:0001193125-26-126276:0
◇ See Remarks · Executives · 26 Feb 2026
17,900 shares @ US$3.87 3.9% of flow Ordinary Shares SEC:0001193125-26-083712:0
◆ Chief Financial Officer · Executives · 5 Feb 2026
45,625 shares 0Ordinary Shares SEC:0001193125-26-047323:0
◆ President and CEO · Executives · 5 Feb 2026
165,000 shares 0Ordinary Shares SEC:0001193125-26-047322:0
◆ See Remarks · Executives · 5 Feb 2026
38,750 shares 0Ordinary Shares SEC:0001193125-26-047319:0
◆ See Remarks · Executives · 5 Feb 2026
45,625 shares 0Ordinary Shares SEC:0001193125-26-047314:0
◇ See Remarks · Executives · 2 Jan 2026
9,375 shares @ US$3.14 1.6% of flow Ordinary Shares SEC:0001193125-26-005195:0
1,470,000 shares @ US$19.00 40.3% of flow Ordinary Shares SEC:0001999371-25-020336:0
Canonical exit: 11 Mar 2026 (T+90) ◇ Director · Executives · 8 Dec 2025
42,000 shares @ US$5.97 69.5% of flow Ordinary Shares SEC:0001193125-25-314742:0
◇ Director · Executives · 8 Dec 2025
7,000 shares @ US$5.97 100.0% of flow Ordinary Shares SEC:0001193125-25-314741:0
▼ Director · Executives · 8 Dec 2025
6,445 shares @ US$12.75 44.6% of flow Ordinary Shares SEC:0001193125-25-314740:0
▼ Director · Executives · 8 Dec 2025
7,494 shares @ US$12.75 32.2% of flow Ordinary Shares SEC:0001193125-25-314739:0
▼ Director · Executives · 8 Dec 2025
12,020 shares @ US$13.09 19.0% of flow Ordinary Shares SEC:0001193125-25-314738:0
◇ See Remarks · Executives · 8 Dec 2025
28,125 shares @ US$3.14 5.3% of flow Ordinary Shares SEC:0001193125-25-314737:0
◇ Chief Financial Officer · Executives · 8 Dec 2025
60,000 shares @ US$2.83 22.5% of flow Ordinary Shares SEC:0001193125-25-314736:0
▼ Director · Executives · 8 Dec 2025
9,600 shares @ US$13.09 100.0% of flow Ordinary Shares SEC:0001193125-25-314735:0
▲ Director · Executives · 13 Nov 2025
1,000 shares @ US$6.6875 0.0% of flow Ordinary Shares SEC:0001231919-25-000499:0
Canonical exit: 11 Feb 2026 (T+90) ▼ Director · Executives · 13 Nov 2025
16,115 shares @ US$6.79 100.0% of flow Ordinary Shares SEC:0001193125-25-283619:0
▼ Director · Executives · 22 Aug 2025
10,000 shares @ US$10.00 14.9% of flow Ordinary Shares SEC:0000950170-25-111568:0
▼ President and CEO · Executives · 22 Aug 2025
217,351 shares @ US$10.098 39.0% of flow Ordinary Shares SEC:0000950170-25-111567:0
◇ Director · Executives · 15 Aug 2025
21,000 shares @ US$9.13 95.1% of flow Ordinary Shares SEC:0000950170-25-110287:0
◆ Director · Executives · 11 Aug 2025
12,700 shares 0Ordinary Shares SEC:0001415889-25-021689:0
◆ Director · Executives · 11 Aug 2025
12,700 shares 0Ordinary Shares SEC:0000950170-25-108289:0
◆ Director · Executives · 11 Aug 2025
12,700 shares 0Ordinary Shares SEC:0000950170-25-108291:0
25 of 80 declarations
Load more (55 remaining) 关于 Wave Life Sciences Ltd. Wave Life Sciences Ltd. 是一家在纳斯达克上市的美国生物技术公司,专注于 RNA 药物,这是一个新兴且可能具有差异化的药物开发领域。该公司成立于 2012 年,其美国总部位于马萨诸塞州剑桥市,使其处于世界领先的生命科学集群之一。Wave 最好被描述为一家临床阶段生物技术公司:它不是一家成熟的商业制药集团,而是一家试图将专有平台科学转化为针对基因定义疾病的高价值疗法的公司。
其商业模式围绕专有的寡核苷酸化学和设计平台构建,最初与 PRISM 相关,现在已扩展到 RNA 编辑和 siRNA 方法。实际上,Wave 正在针对那些具有强大基因验证可以支持更清晰临床假设,并且如果成功,可以带来高溢价产品经济效益的适应症。该公司领先且最受关注的项目是用于肥胖症的 WVE-007、用于 α-1 抗胰蛋白酶缺乏症 (AATD) 的 WVE-006,以及用于 PNPLA3 相关肝病的 WVE-008。Wave 还保留了杜氏肌营养不良症和亨廷顿病方面的临床和研究项目,使其在专注于专业、高度未满足需求领域的同时,拥有更广泛的科学足迹。
从竞争角度来看,Wave 在一个非常拥挤的创新领域运营,与其他的 RNA 疗法开发者以及专注于疾病的生物技术同行竞争。其投资案例由平台差异化、靶点验证以及持久或不频繁给药方案的潜力驱动,这在慢性病中尤其具有吸引力。该公司还保持国际运营结构,在美国和日本开展研发活动,这强化了其作为全球化生物技术平台而非纯粹的美国本土公司的地位。
近期里程碑事件非常重要。在 2025 年和 2026 年,Wave 报告了 WVE-007 和 WVE-006 令人鼓舞的临床更新,强调了其加速 RNA 编辑产品组合的计划,并在 2026 年初通过大规模融资增强了流动性。该公司还在 2026 年宣布从 GSK 收回 WVE-006 的全部权利,这可能会提高战略灵活性和长期价值创造。对于投资者而言,Wave 仍然是一个经典的高风险/高回报生物技术故事:技术雄心勃勃,科学上引人入胜,但仍依赖于成功的临床执行、监管进展和持续的资本获取。