No insider purchase over the last 90 days. The latest was filed 05 Mar 2026.
Every trade that managers of Akebia Therapeutics, Inc. disclose to SEC (Form 4) is tracked on this page. The company sits in the Healthcare & Pharma sector. From 18 October 2025 to 18 October 2026, the disclosure feed for Akebia Therapeutics, Inc. logged 22 filings by 13 insiders.
The record shows 1 purchase on the open market worth €75k, made by 1 insider, against 7 sales worth €246k by 6 insiders. No amount is published for 1 filing, which the totals therefore leave out. Open-market purchases are the filings investors watch most closely, because the insider pays for the shares out of pocket. At €75k, the purchase published on 5 March 2026 by Butler John P. is the largest of the period. Among those who bought: 1 chief executive.
Across the 5,816 companies tracked on its exchange, the median is 19 filings; at 22 filings, this issuer sits above that mark. Our records for Akebia Therapeutics, Inc. go back to 2016, with 1 purchase and 47 sales on the open market in total. In its latest annual report filed with the SEC (10-K, fiscal year ended 31 December 2025), the company reported revenue of 236.2 m USD and net income of -5.3 m USD.
The clock since the last published purchase (5 March 2026) now reads 227 days. The median gap between a trade and its publication by SEC (Form 4) is 4 days. US insiders must file a Form 4 within two business days of a trade. Sales are harder to read than purchases, since they often meet personal needs such as tax or diversification.
Elsewhere in the same sector, our signals recently picked up insider purchases at Cooper Companies, Inc. and Anixa Biosciences Inc. This summary is built from SEC (Form 4) disclosures alone and does not predict where the share price will go.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended December 2025 · cache
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Akebia Therapeutics, Inc. is a U.S.-based biopharmaceutical company listed on the NASDAQ in the United States, with a focused franchise in kidney disease and kidney-disease-related conditions. Founded in 2007, the company has developed as an integrated biotech platform combining clinical development, regulatory work, commercialization, and market access execution. Its headquarters are in Cambridge, Massachusetts, placing it in one of the most established life-science clusters in the country.
Akebia’s business model is centered on two main pillars: commercial products and pipeline development. Its lead commercial asset is Vafseo (vadadustat), an oral therapy for certain adults with anemia due to chronic kidney disease, which has become the company’s key growth driver as it continues to expand in the U.S. market. Akebia also markets Auryxia (ferric citrate), a renal product used to treat hyperphosphatemia in patients with chronic kidney disease on dialysis and iron deficiency anemia in certain non-dialysis CKD patients. These marketed products give Akebia a revenue base, but they also create concentration risk, especially given generic competition and reimbursement sensitivity.
From a competitive standpoint, Akebia is a specialist rather than a broad nephrology leader. Its position is shaped by deep therapeutic expertise in kidney disease, a commercial infrastructure built around renal prescribers, and a pipeline intended to extend the company’s relevance beyond the first wave of launches. In this segment, differentiation depends on clinical utility, safety, dosing convenience, and access to the appropriate patient population. Akebia’s strategy is therefore less about scale and more about targeted execution in a high-need, medically complex market.
Recent developments underscore that the company is still in a transition phase. In early 2026, Akebia reported full-year 2025 results and commercial highlights around Vafseo’s launch, while also discussing a broader kidney-disease pipeline. In April 2026, the company held a virtual R&D Day focused on its kidney disease programs. Management also indicated that Auryxia revenue is expected to face pressure from expanding generic competition in 2026. For investors, Akebia represents a small-cap U.S. biotech with a commercial plus pipeline profile, where the investment case hinges on Vafseo uptake, Auryxia resilience, and the pipeline’s ability to create additional growth options.
Purchases our model currently ranks for the recommendations list.
All recommendations| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 236.2 m USD | -5.3 m USD | -0.02 USD | 10-K |
| Dec 2024 | 160.2 m USD | -69.4 m USD | -0.33 USD | 10-K |
| Dec 2023 | 194.6 m USD | -51.9 m USD | -0.28 USD | 10-K |
| Dec 2022 | 292.5 m USD | -94.2 m USD | -0.52 USD | 10-K |
| Dec 2021 | 211.7 m USD | -282.0 m USD | -1.70 USD | 10-K/A |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.