Weiss Patrick

About Weiss Patrick

Patrick Weiss is an experienced life sciences executive best known for his role as Chief Operating Officer at Twist Bioscience Corp. At Twist, he was promoted to COO in January 2020 after helping build the company’s operational infrastructure from its earliest days. The company described his contribution as central to turning a complex manufacturing process into a robust commercial platform, supporting Twist’s broader push for growth and scale in the U.S. public markets. In 2022, he transitioned out of his operational role into a strategic adviser position and later joined ARCH Venture Partners as a Venture Partner. His earlier career includes serving as CEO of Operon Biotechnologies, a company focused on nucleic acid synthesis, sequencing, and bioinformatics services. He also held senior responsibilities at Qiagen as Vice President, Gene Silencing, where he managed RNA synthesis and siRNA-related product areas. Earlier still, he founded and led Xeragon, a company active in RNA synthesis and related products. Across these roles, Weiss built a career around scaling scientific businesses, improving operational execution, and translating advanced biotechnology platforms into commercial organizations. At Twist, that experience was especially relevant as the company expanded from a small startup into a publicly traded synthetic biology platform. Overall, his background reflects deep expertise in life sciences operations, manufacturing scale-up, nucleic acid technologies, and company building, with a track record spanning startup leadership, corporate operations, and venture investing.