Twist Bioscience Corp, founded in 2013, is a Healthcare & Pharma company based in San Francisco, United States. Its directors and officers file their transactions with SEC (Form 4). In the past year (20 October 2025 to 20 October 2026), 214 filings came from 21 insiders.
All open-market trades in the period are sales: 129 sales worth €107.5M, by 10 insiders, with no purchase on record. Biggest ticket of the year: €32.0M, sold by Leproust Emily M. and made public on 21 September 2026 (0.41% of market cap).
Typically, a trade is published a median of 2 days after it takes place. For comparison, the SEC allows two business days to file a Form 4. Selling is not necessarily a view on the stock: liquidity needs and diversification are common motives.
Across the 5,813 companies tracked on its exchange, the median is 19 filings; at 214 filings, this issuer sits above that mark. Looking back to 2021, when coverage begins, insiders filed 2 purchases and 334 sales. For the fiscal year to 30 September 2025, the annual 10-K puts revenue at 376.6 m USD and net income at -77.7 m USD.
In the same sector, recent insider purchases at Anixa Biosciences Inc and Vivos Inc also feature in our signals. Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
+4 other insiders
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate Twist Bioscience Corp Buy (bullish), based on 12 analysts. Average price target: US$163.67.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended September 2025 · cache
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Twist Bioscience Corp. (NASDAQ: TWST) is a United States-based life sciences company listed on the NASDAQ market in the United States. Founded in 2013 and headquartered in South San Francisco, California, Twist has built its business around a proprietary silicon-based DNA synthesis platform. That platform is designed to manufacture synthetic DNA at scale with speed, precision, and potentially lower unit economics than many legacy approaches. The company serves customers across research life sciences, biopharma, diagnostics, agriculture, and broader synthetic biology applications.
Twist’s core business is centered on nucleic acid synthesis and genomics-enabled tools. Its product portfolio includes synthetic genes, gene fragments, library preparation kits for sequencing workflows, target enrichment products, oncology-focused next-generation sequencing panels, and other consumables used in molecular biology and genomic research. In practical terms, Twist is not just a reagent supplier; it is a platform company that supports the upstream workflows used by academic labs, biotech firms, pharmaceutical companies, and translational research centers. This makes the business strategically important in workflows where sequence accuracy, turnaround time, and scalability matter.
From a competitive standpoint, Twist operates in a highly specialized and innovation-driven market. Its differentiation comes from its silicon-based synthesis technology, which is a meaningful industrial advantage in a sector where customers increasingly demand higher throughput, more complex designs, and reliable supply. The company competes on product performance, workflow integration, and breadth of applications, especially in next-generation sequencing, oncology research, and nucleic-acid therapeutics research. Its growing portfolio suggests a deliberate move toward more integrated, higher-value solutions rather than standalone DNA orders.
Recent company developments have reinforced that strategy. In 2025 and early 2026, Twist announced multiple product launches, including new plasmid preparation offerings, next-generation library preparation kits, expanded complex gene capabilities, and broader oncology genomic profiling solutions. Twist also expanded and advanced its collaboration with Element Biosciences to develop integrated sequencing workflows, underscoring its ambition to become more deeply embedded in the NGS ecosystem. These actions indicate a continued focus on product innovation, broader addressable markets, and deeper penetration into applied genomics workflows.
For investors, Twist remains a growth-oriented biotechnology tools company with exposure to research spending cycles and biotech funding conditions. At the same time, its differentiated platform, recurring consumables model, and expanding product suite position it as a notable specialist in synthetic biology and genomics tools within the United States market.
Purchases our model currently ranks for the recommendations list.
All recommendationsInsider filings
Over the last 90 days, 112 filings published between 23 July and 9 October 2026: 66 sales for €98.5M. 46 other filings (not open-market purchases or sales: grants, options, plans, sale notices, block transfers). Largest amounts: Leproust Emily M. (Chief Executive Officer), sales of €79.6M; Finn Patrick John (President and COO), sales of €12.8M; Green Paula (SVP of Human Resources), sales of €2.0M.
Summary written automatically from public filings, without human review. General information, identical for every reader: it is not investment advice or a recommendation to buy or sell. Investing involves a risk of capital loss. Generated on 14 October 2026 (UTC)
Headquarters: San Francisco, United States · Founded: 2013 · Wikipedia article
Source: Wikidata (CC0).
| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Sep 2025 | 376.6 m USD | -77.7 m USD | -1.30 USD | 10-K |
| Sep 2024 | 313.0 m USD | -208.7 m USD | -3.60 USD | 10-K |
| Sep 2023 | 245.1 m USD | -204.6 m USD | -3.60 USD | 10-K |
| Sep 2022 | 203.6 m USD | -217.9 m USD | -4.04 USD | 10-K |
| Sep 2021 | 132.3 m USD | -152.1 m USD | -3.15 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.
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