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Maria-Luisa Maccecchini

Executive
Chief Executive Officer
Annovis Bio, Inc.CALMARE THERAPEUTICS Inc
Insider activity · 24 months1 buy0 salesCumulative net flow
Total declarations
19
Companies
2
▲ Purchases (5 ops.)
€617k
▼ Sales (0 ops.)
—

Latest filing published 12 Nov 2025 for Annovis Bio, Inc., €172k.

Filing timeline

BuySale
Maria-Luisa Maccecchini

Insider track record

Disclosed buys
5
Disclosed sells
0
Signal history

Closed purchases

Market purchases
5
Positive at T+90
33%
Median T+90
-40.4%

Based on 3 purchases whose 90-day window has closed (published at least 91 days ago), the same population our ranking model reads.

Purchases by company

Since each purchase

  • Filed 12 Nov 2025 · 362 days ago · €172k
    -56.3%
    Entry US$2.29 · Close 23 Oct 2026 US$1.00
  • Filed 13 Oct 2021 · 1853 days ago · €430k
    -59.4%
    Entry US$30.81 · Close at T+365 US$12.50
  • Filed 05 Feb 2020 · 2468 days ago · €8,704
    +175.3%
    Entry US$6.16 · Close at T+365 US$16.96

Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.

Maria-Luisa Maccecchini: trading record in brief

Maria-Luisa Maccecchini is a declared insider at 2 companies (chief executive); the most frequent names are Annovis Bio, Inc. and CALMARE THERAPEUTICS Inc. Over a trading history stretching from 4 January 2006 to 28 October 2025, the count stands at 19 filings.

The open-market record is one-sided, with 5 purchases worth €617k and not one sale. Open-market purchases are the filings investors watch most closely, because the insider pays for the shares out of pocket. The rest of the record consists of 6 share grants and 2 option exercises. In 2025 alone, the filings show 1 purchase and no sales.

Half of the purchases are above €8,704 and half below. Of 3 purchases, 3 formed part of a group of insiders buying within 30 days of each other. A cluster is several different insiders buying the same stock within a short window, a pattern studied more closely than a single purchase. Looking at 3 purchases old enough to measure, the stock rose over the following 90 days in 33% of cases; the median change was -40.4%. Past outcomes like these are no guarantee of what comes next.

On 12 November 2025 came the latest disclosure, an open-market purchase for €172k in Annovis Bio, Inc. Filings reach the SEC (Form 4) feed a median of 4 days after the trade. For comparison, the SEC allows two business days to file a Form 4. These figures are compiled from regulatory filings published by SEC (Form 4). They describe what insiders did and are not a recommendation.

Companies and markets linked to Maria-Luisa Maccecchini

Open company profiles for insider transactions, fundamentals and analyst consensus when available.

Declarations19 total

19 of 19 declarations