No insider purchase over the last 90 days. The latest, by STERN ADAM K, was filed 24 Aug 2020.
Matinas BioPharma Holdings, Inc., classified in the Healthcare & Pharma sector, is a listed company. Its insiders report their share dealings to SEC (Form 4). Between 22 October 2025 and 22 October 2026, 1 insider published 3 filings.
No open-market purchase or sale appears among the filings, only grants, plan transactions and other operations. Such operations are usually part of compensation schedules, which makes them a weaker signal than an open-market trade.
Compared with its exchange (2,023 companies, median 41 filings), a count of 3 filings is below the norm. Over the whole record (from 2017), the tally stands at 28 purchases and no sales.
No insider has bought Matinas BioPharma Holdings, Inc. shares on the open market in the past twelve months. Between a trade and the moment it shows up on SEC (Form 4), the median delay is 34 days. For comparison, the SEC allows two business days to file a Form 4.
Other companies in the same sector with recent insider buying flagged by our signals: Xenon Pharmaceuticals Inc. and Vivos Inc. Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
FY ended December 2025 · cache
25 of 121 declarations
Matinas BioPharma Holdings, Inc. (MTNB) is a U.S.-listed biopharmaceutical company traded on NYSE American, headquartered in Bedminster, New Jersey, United States. Founded in May 2013, the company was built around a clear thesis: improve the delivery of hard-to-formulate anti-infective therapies through its proprietary lipid nanocrystal (LNC) platform, also described in its materials as a cochleate/encochleated delivery approach. For French-speaking investors, this is a classic clinical-stage biotechnology story: high R&D intensity, limited current commercial visibility, and a valuation that depends heavily on clinical, regulatory, and financing milestones. ([matinasbiopharma.com](https://www.matinasbiopharma.com/investors/sec-filings/annual-reports/content/0001493152-23-007726/0001493152-23-007726.pdf?utm_source=openai))
The company’s pipeline is currently centered on two lead programs. MAT2203 is Matinas’ flagship asset: an oral formulation of amphotericin B, a potent antifungal agent that is traditionally administered intravenously. The company is developing MAT2203 to potentially provide a safer, more convenient oral option for serious fungal infections, including invasive aspergillosis. MAT2501 is the second core program: an oral formulation of amikacin aimed at difficult bacterial infections, including nontuberculous mycobacteria (NTM) and other resistant pathogens. Matinas also positions its LNC platform as a broader enabling technology that could support future programs in inflammation and oncology. ([matinasbiopharma.com](https://www.matinasbiopharma.com/lnc-technology/mat2203?utm_source=openai))
From a competitive perspective, Matinas is not a commercial-stage pharmaceutical company with approved products and recurring sales. Instead, it seeks to differentiate itself through drug-delivery innovation in anti-infectives, with the goal of converting IV-only medicines into oral therapies that may reduce toxicity and improve patient convenience. That proposition is scientifically attractive, but execution remains the key risk: the company still depends on clinical data, regulatory interactions, and potential strategic partnerships to advance its pipeline. ([matinasbiopharma.com](https://www.matinasbiopharma.com/investors/news-events/press-releases/detail/248/matinas-biopharmas-lead-antibacterial-development?utm_source=openai))
Recent developments matter materially for the equity story. In April 2026, Matinas disclosed that it had received a notice of non-compliance from NYSE American regarding continued listing standards, tied to stockholders’ equity and a history of losses. During 2025, the company focused mainly on board refreshment and governance changes, while continuing to highlight MAT2203 as its lead program. For investors, this creates a profile with meaningful scientific upside, but also elevated balance-sheet and listing-risk considerations. ([matinasbiopharma.com](https://www.matinasbiopharma.com/investors/sec-filings/all-sec-filings/content/0001493152-26-015170/form8-k.htm?utm_source=openai))
Purchases our model currently ranks for the recommendations list.
All recommendations| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2023 | 1.1 m USD | -22.9 m USD | -5.28 USD | 10-K |
| Dec 2022 | 3.2 m USD | -21.0 m USD | -0.10 USD | 10-K |
| Dec 2021 | 33,000 USD | -23.3 m USD | n.d. | 10-K |
| Dec 2020 | 158,333 USD | -22.4 m USD | n.d. | 10-K/A |
| Dec 2019 | 89,812 USD | -17.4 m USD | n.d. | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.