No insider purchase over the last 90 days. The latest was filed 13 May 2025.
Ligand Pharmaceuticals Inc belongs to the Healthcare & Pharma sector. Filings by its managers are published through SEC (Form 4). Over the twelve months to 18 October 2026, the company's managers filed 101 filings, from 17 insiders.
Only sales appear on the open market, 54 sales in all totalling €17.2M, filed by 8 insiders. The amount is not disclosed for 2 filings. The largest single trade was a sale of €8.0M by Espinoza Octavio, published on 14 August 2026, equal to 0.15% of the market capitalisation.
For context, the typical company on the same exchange (median of 5,458 companies) published 22 filings over the same period, against 101 filings here. The full history, which starts in 2016, counts 5 purchases against 82 sales. In its latest annual report filed with the SEC (10-K, fiscal year ended 31 December 2025), the company reported revenue of 268.1 m USD and net income of 124.5 m USD.
The median gap between a trade and its publication by SEC (Form 4) is 2 days. Section 16 rules allow two business days to file each Form 4. Sales are harder to read than purchases, since they often meet personal needs such as tax or diversification.
In the same sector, recent insider purchases at Anixa Biosciences Inc and Vivos Inc also feature in our signals. Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
+3 other insiders
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate Ligand Pharmaceuticals Inc Strong Buy (bullish), based on 12 analysts. Average price target: US$344.25.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended December 2025 · cache
25 of 280 declarations
Ligand Pharmaceuticals Incorporated (ticker LGND) is a U.S.-based biopharmaceutical company listed on the Nasdaq Global Market in the United States. Its business model is materially different from that of a traditional drug developer: Ligand operates primarily as a biopharmaceutical royalty aggregator, late-stage development financier, and licensor of proprietary technology platforms to industry partners. The company, whose operational headquarters are in Jupiter, Florida, builds a diversified stream of revenue from product royalties, milestone payments, formulation-material sales, and selected intellectual-property investment activities.
Historically, Ligand has pursued an asset-light model focused on funding, acquiring, or monetizing economic rights in partnered biopharmaceutical programs rather than carrying the full cost burden of R&D and commercialization internally. Today, the company highlights two core technology platforms: Captisol®, a chemically modified cyclodextrin designed to improve drug solubility and stability, and NITRICIL®, an IP platform added through the 2023 Novan acquisition. These platforms support licensing activity and can generate royalty income as partners advance and commercialize medicines.
Ligand’s portfolio includes multiple commercial royalty assets as well as a broader set of development-stage programs, giving it exposure to several clinical and regulatory cycles without depending on a single blockbuster product. Partnered products often cited by the company include Kyprolis®, FILSPARI®, Ohtuvayre®, and Tzield®, although the exact economics and contribution profile vary by agreement and maturity stage. This diversification is a key competitive advantage versus more binary biotech models, while still leaving Ligand meaningfully exposed to its partners’ clinical and commercial execution.
From a market-positioning standpoint, Ligand is a niche but important participant in the U.S. biopharma royalty ecosystem. Its value proposition rests on disciplined capital allocation, relatively low infrastructure requirements, and the ability to extract value from intellectual-property assets without running a full-scale pharmaceutical operating model. The company also reinforced this positioning in 2026 by announcing a proposed acquisition of XOMA Royalty, a move intended to accelerate profit growth and strengthen Ligand’s standing as a consolidator in the royalty-aggregation space.
Geographically, Ligand’s corporate base is in the United States, while its partners commercialize products globally. Recent notable developments include first-quarter 2026 results released on May 7, 2026, new business development appointments, and the XOMA Royalty transaction announcement. For investors, LGND remains a distinctive healthcare name on the Nasdaq: part biotech, part capital allocator, and part royalty platform, with its long-term upside tied to partner pipeline success, deal-making discipline, and the durability of its IP-backed revenue streams.
Purchases our model currently ranks for the recommendations list.
All recommendations| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 268.1 m USD | 124.5 m USD | 6.13 USD | 10-K |
| Dec 2024 | 167.1 m USD | -4.0 m USD | -0.22 USD | 10-K |
| Dec 2023 | 131.3 m USD | 52.2 m USD | 2.94 USD | 10-K |
| Dec 2022 | 196.2 m USD | -33.4 m USD | -1.98 USD | 10-K |
| Dec 2021 | 241.5 m USD | 57.1 m USD | 3.31 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.