XT Xilio Therapeutics, Inc. Stock: price and management transactions · United States · SEC (Form 4)Follow the Xilio Therapeutics, Inc. stock price and the full management transaction log of the company, a listed equity based in United States. Shares trade on the US market, under the supervision of SEC (Form 4). Operating in the Healthcare & Pharma sector, Xilio Therapeutics, Inc. has recorded 31 reports. Market capitalisation: €56.9m. The latest transaction was disclosed on 30 March 2026 (Acquisition). Among the most active insiders: Atlas Venture Fund XI, L.P.. The full history is openly available.
This score ranks the purchase within its own market. No market currently meets the historical allocation criteria, so signals remain watch-only. Not investment advice.
Fundamental score
Ranked 28,830 of 29,062 companies
FCF yld -9.7%
Earn yld -62%
EV/EBITDA ·
ROE -75%
Gross mgn ·
Net mgn -80%
Debt/EBITDA ·
Pillars 2/3
Transparent value + quality ranking, distinct from the insider signal.
Σ Sigma AI Analysis Fundamental view, insider signal, bull and bear case, synthesis.
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Last declaration on 30 March 2026
All Executives31 Thresholds0 Prospectus0 Other0
Declarations 31 total
▲ Director · Executives · 26 Mar 2026
5,000 shares @ US$8.79 58.7% of flow Common Stock SEC:0001193125-26-131745:0
Canonical exit: 24 Jun 2026 (T+90) ◇ CHIEF MEDICAL OFFICER · Executives · 1 Jan 2026
16,625 shares Common Stock SEC:0001193125-26-002520:0
◇ SVP, FINANCE AND ACCOUNTING · Executives · 1 Jan 2026
5,000 shares Common Stock SEC:0001193125-26-002518:0
◇ Chief Financial Officer · Executives · 1 Jan 2026
19,375 shares Common Stock SEC:0001193125-26-002517:0
◇ PRESIDENT AND CEO · Executives · 1 Jan 2026
44,250 shares Common Stock SEC:0001193125-26-002512:0
▲ Director · Executives · 16 Jun 2025
45,000 shares @ US$0.686 100.0% of flow Common Stock SEC:0001415889-25-017705:0
Canonical exit: 14 Sept 2025 (T+90) ▲ PRESIDENT AND CEO · Executives · 16 Jun 2025
36,289 shares @ US$0.6801 100.0% of flow Common Stock SEC:0001415889-25-017704:0
Canonical exit: 14 Sept 2025 (T+90) ◇ CHIEF MEDICAL OFFICER · Executives · 1 Jan 2025
16,625 shares Common Stock SEC:0001415889-25-000406:0
◇ SVP, FINANCE AND ACCOUNTING · Executives · 1 Jan 2025
5,000 shares Common Stock SEC:0001415889-25-000404:0
◇ PRESIDENT AND CEO · Executives · 1 Jan 2025
44,250 shares Common Stock SEC:0001415889-25-000405:0
◇ Chief Financial Officer · Executives · 1 Jan 2025
19,375 shares Common Stock SEC:0001415889-25-000407:0
1,759,978 shares @ US$1.04 83.6% of flow Common Stock SEC:0001062993-24-020910:0
Canonical exit: 18 Mar 2025 (T+90) 485,250 shares @ US$0.76 16.4% of flow Common Stock SEC:0001062993-24-008004:0
Canonical exit: 1 Jul 2024 (T+90) 733 shares @ US$0.64 11.7% of flow Common Stock SEC:0001209191-24-003031:0
1,566 shares @ US$0.87 33.4% of flow Common Stock SEC:0001209191-24-001655:0
▼ 10% Owner · Executives · 11 Jan 2024
569 shares @ US$0.87 12.1% of flow Common Stock SEC:0001209191-24-001655:1
▼ 10% Owner · Executives · 12 Jan 2024
1,540 shares @ US$0.83 31.3% of flow Common Stock SEC:0001209191-24-001655:2
▼ 10% Owner · Executives · 12 Jan 2024
560 shares @ US$0.83 11.4% of flow Common Stock SEC:0001209191-24-001655:3
13,458 shares @ US$9.6206 0.23% mcap 50.0% of flow Common Stock SEC:0000899243-21-047829:0
Canonical exit: 8 Mar 2022 (T+90) 998,544 shares Common Stock SEC:0000899243-21-042710:0
756,472 shares Common Stock SEC:0001193805-21-001508:0
218,705 shares Common Stock SEC:0000318989-21-000078:0
789,473 shares Common Stock SEC:0000315066-21-001812:0
998,544 shares Common Stock SEC:0000899243-21-041838:0
1,372,998 shares Common Stock SEC:0001104659-21-130026:0
25 of 31 declarations
Load more (6 remaining) 关于 Xilio Therapeutics, Inc. Xilio Therapeutics, Inc. (NASDAQ: XLO) 是一家临床阶段的生物技术公司,总部位于美国马萨诸塞州沃尔瑟姆。对于欧洲投资者而言,Xilio 最好被理解为一家专注于下一代免疫肿瘤学的小盘美国生物技术公司,特别是旨在改善癌症治疗治疗窗口的掩蔽或肿瘤激活疗法。该公司围绕一个专有的掩蔽平台建立,旨在将药物活性集中在肿瘤微环境中,从而减少全身暴露并可能提高耐受性。Xilio 在美国纳斯达克市场交易,这使其明确属于通常由临床催化剂、合作更新和融资需求驱动的美国生物技术公司群体。([ir.xiliotx.com](https://ir.xiliotx.com/news-releases/news-release-details/xilio-therapeutics-announces-pipeline-and-business-updates-11/?utm_source=openai))
Xilio 的商业模式结合了内部药物开发与合作和许可协议,这些协议可以产生里程碑付款和其他非稀释性资金。该公司的核心战略资产是其经过临床验证的掩蔽技术,该技术用于设计免疫肿瘤疗法,目标是实现比传统方法更强的肿瘤选择性。其目前的管线包括 XTX501,这是一个掩蔽的双特异性 PD-1 / IL-2 项目,管理层将其描述为实体瘤联合治疗方案的潜在骨干疗法,以及 XTX601,一个靶向 CLDN18.2 的掩蔽 T 细胞衔接器。Xilio 还在推进其他掩蔽项目,这使其拥有一个平台故事,而不是依赖单一资产。([ir.xiliotx.com](https://ir.xiliotx.com/news-releases/news-release-details/xilio-therapeutics-reports-first-quarter-2026-financial-results?utm_source=openai))
在竞争方面,Xilio 占据了一个有吸引力但风险极高的利基市场。其潜在优势在于其能够在药物到达肿瘤之前掩蔽活性成分,这在毒性历来限制细胞因子和 T 细胞衔接器效用的实体瘤中可能很重要。与此同时,该公司与更大的生物制药集团和资金更充足的生物技术同行竞争,这些公司也在开发双特异性抗体、工程化细胞因子和 T 细胞衔接器平台。因此,Xilio 的估值在很大程度上取决于早期临床验证、IND 启动进展、监管执行以及获得合作或额外资金的能力。与许多临床阶段的生物技术公司一样,它尚未拥有商业产品基础,因此投资案例仍然主要是二元和事件驱动的。([ir.xiliotx.com](https://ir.xiliotx.com/news-releases/news-release-details/xilio-therapeutics-announces-pipeline-and-business-updates-11/?utm_source=openai))
近期亮点包括 2026 年第一季度财务业绩、在 AACR 2026 上展示的 XTX601 新临床前数据,以及 XTX501 持续推进,预计将于 2026 年提交 IND 申请。该公司还在 2026 年初报告了管线和业务更新,并曾于 2025 年完成 50 million 美元的公开发行,以支持开发和一般公司用途。总的来说,Xilio 仍然是一个高风险、高催化剂的美国生物技术故事:科学上具有差异化,仍处于商业化前阶段,并且在未来几个季度高度依赖执行里程碑。([ir.xiliotx.com](https://ir.xiliotx.com/news-releases/news-release-details/xilio-therapeutics-reports-first-quarter-2026-financial-results?utm_source=openai))