VN Vigil Neuroscience, Inc. Stock: price and insider trades · United States · SEC (Form 4)Track the Vigil Neuroscience, Inc. stock price and the full management transaction log of the company, a listed equity based in United States. Shares trade on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Vigil Neuroscience, Inc. has published 39 reports. The latest transaction was reported on 7 August 2025 (Disposition). Among the most active insiders: Magovcevic-Liebisch Ivana. All data is openly available.
€199,117
12 ops.
Buy Volume
This score ranks the purchase within its own market. No market currently meets the historical allocation criteria, so signals remain watch-only. Not investment advice.
Σ Sigma AI Analysis Fundamental view, insider signal, bull and bear case, synthesis.
AI analysis generation is paused.
Last declaration on 7 August 2025
All Executives39 Thresholds0 Prospectus0 Other0
Declarations 39 total
4,808,896 shares Common Stock SEC:0001415889-25-021282:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102504:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102498:0
● Chief Financial Officer · Executives · 5 Aug 2025
4,000 shares Common Stock SEC:0000950170-25-102496:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102492:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102491:0
● President and CEO · Executives · 5 Aug 2025
222,687 shares Common Stock SEC:0000950170-25-102487:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102485:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102476:0
● Director · Executives · 5 Aug 2025
5,000 shares Common Stock SEC:0000950170-25-102471:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077278:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077274:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077269:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077276:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077272:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077268:0
◆ Director · Executives · 22 May 2025
5,000 shares 0Common Stock SEC:0000950170-25-077267:0
▲ Director · Executives · 19 Dec 2024
12,000 shares @ US$1.71 100.0% of flow Common Stock SEC:0000950170-24-138619:0
Canonical exit: 19 Mar 2025 (T+90) ▲ President and CEO · Executives · 19 Dec 2024
5,000 shares @ US$1.68 14.8% of flow Common Stock SEC:0000950170-24-138617:0
Canonical exit: 19 Mar 2025 (T+90) ▲ President and CEO · Executives · 18 Dec 2024
5,000 shares @ US$1.67 14.5% of flow Common Stock SEC:0000950170-24-138012:0
Canonical exit: 18 Mar 2025 (T+90) ▲ President and CEO · Executives · 5 Dec 2024
5,000 shares @ US$2.34 20.3% of flow Common Stock SEC:0000950170-24-133755:0
Canonical exit: 5 Mar 2025 (T+90) ▲ President and CEO · Executives · 20 Nov 2023
4,000 shares @ US$3.75 25.1% of flow Common Stock SEC:0000950170-23-065228:0
Canonical exit: 18 Feb 2024 (T+90) ◇ Chief Medical Officer · Executives · 18 Nov 2022
300 shares @ US$1.89 4.1% of flow Common Stock SEC:0000899243-22-036831:0
▲ Director · Executives · 16 May 2022
21,802 shares @ US$2.7622 74.6% of flow Common Stock SEC:0000899243-22-018491:0
Canonical exit: 14 Aug 2022 (T+90) ▲ SVP, Head of Early Development · Executives · 5 May 2022
1,500 shares @ US$4.00 100.0% of flow Common Stock SEC:0000899243-22-017015:0
Canonical exit: 3 Aug 2022 (T+90) 25 of 39 declarations
Load more (14 remaining) 关于 Vigil Neuroscience, Inc. Vigil Neuroscience, Inc. 是一家在美国纳斯达克上市的生物制药公司,股票代码为 VIGL。公司总部位于美国马萨诸塞州沃特敦,是一家临床阶段的生物技术公司,通过以小胶质细胞为中心的策略专注于神经退行性疾病。Vigil 成立于 2020 年,其理念是恢复小胶质细胞功能可能有助于解决罕见和更广泛的神经退行性疾病。其科学定位通过专注于大脑中的特定免疫通路,使其与一般的神经学公司区分开来。([vigilneuro.com](https://www.vigilneuro.com/index?utm_source=openai))
Vigil 的核心管线围绕两个主要项目展开。主要临床资产 iluzanebart,也称为 VGL101,是一种完全人源化的单克隆抗体激动剂,靶向 TREM2,TREM2 是一种参与维持小胶质细胞健康和对环境信号反应的受体。Iluzanebart 已被开发用于 ALSP(成人发病性轴突球样变伴色素性胶质细胞白质脑病),这是一种罕见且严重的神经退行性疾病,Vigil 已报告临床和生物标志物数据支持其疾病修饰假说。第二个主要项目 VG-3927 是一种小分子 TREM2 激动剂,设计用于常见的神经退行性疾病,最初专注于基因定义的阿尔茨海默病患者亚群。([investors.vigilneuro.com](https://investors.vigilneuro.com/news-releases/news-release-details/vigil-neuroscience-provides-update-clinical-development-strategy/?utm_source=openai))
从市场定位来看,Vigil 是一家在神经科学药物开发新兴领域运营的利基型高科技公司。这种定位提供了潜在的差异化,但也伴随着典型的生物技术风险特征:集中的管线风险、临床和监管不确定性以及持续的资本需求。该公司 2024 年年度报告指出,自成立以来一直亏损,并且对其持续经营能力存在重大疑问,这突显了单一平台临床生物技术公司常见的财务脆弱性。([sec.gov](https://www.sec.gov/Archives/edgar/data/1827087/000095017025038329/vigl-20241231.htm))
最近的进展主要集中在战略性并购。2025 年 5 月 21 日,Vigil 宣布了一项最终合并协议,根据该协议,赛诺菲同意以每股 8.00 美元的现金收购该公司,预计将于 2025 年第三季度完成交易。赛诺菲还指出,已于 2024 年 6 月对 Vigil 进行了 40 million 美元的战略投资。在交易宣布之前,Vigil 一直在报告 2025 年关于其 2024 年业绩和 TREM2 项目进展的更新,包括 iluzanebart 的 IGNITE 研究和 VG-3927 的持续工作。因此,对于投资者而言,VIGL 最好被理解为一家在美国纳斯达克上市的临床生物技术公司,其独立股权故事受到赛诺菲交易的严重影响。([nasdaq.com](https://www.nasdaq.com/press-release/vigil-neuroscience-enters-definitive-merger-agreement-be-acquired-sanofi-2025-05-21))