Synlogic, INC. Stock: price and management transactions · United States · SEC (Form 4)Follow the Synlogic, INC. share price and the full insider trade history of the company, a listed equity based in United States. Shares trade on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Synlogic, INC. has logged 17 reports. Market capitalisation: €7.4m. The latest transaction was disclosed on 31 October 2025 (Cession). Among the most active insiders: Dooley Mary Beth. All data is free.
€44,656
11 ops.
Sell Volume
This score ranks the purchase within its own market. No market currently meets the historical allocation criteria, so signals remain watch-only. Not investment advice.
Σ Sigma AI Analysis Fundamental view, insider signal, bull and bear case, synthesis.
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Last declaration on 31 October 2025
All Executives17 Thresholds0 Prospectus0 Other0
Declarations 17 total
▼ See Remarks below · Executives · 29 Oct 2025
157 shares @ US$1.81 6.9% of flow Common Stock SEC:0001193125-25-260649:0
◆ Director · Executives · 26 Apr 2025
15,000 shares 0Common Stock SEC:0000950170-25-060253:0
◆ Director · Executives · 26 Apr 2025
15,000 shares 0Common Stock SEC:0000950170-25-060267:0
▼ See Remarks below · Executives · 2 Apr 2025
144 shares @ US$1.20 4.8% of flow Common Stock SEC:0000950170-25-050478:0
▼ See Remarks below · Executives · 3 Feb 2025
2,107 shares @ US$1.33 82.9% of flow Common Stock SEC:0000950170-25-013831:0
▼ Head of Finance · Executives · 29 Oct 2024
79 shares @ US$1.40 3.1% of flow Common Stock SEC:0000950170-24-119194:0
▼ Head of Finance · Executives · 2 Apr 2024
188 shares @ US$1.73 9.2% of flow Common Stock SEC:0000950170-24-041790:0
▼ Chief Operating Officer · Executives · 2 Apr 2024
372 shares @ US$1.73 6.0% of flow Common Stock SEC:0000950170-24-041787:0
▼ Chief Financial Officer · Executives · 3 Apr 2023
2,553 shares @ US$0.5758 12.0% of flow Common Stock SEC:0000899243-23-010714:0
▼ Chief Operating Officer · Executives · 3 Apr 2023
6,438 shares @ US$0.5758 34.3% of flow Common Stock SEC:0000899243-23-010716:0
▼ See Remarks · Executives · 3 Apr 2023
19,042 shares @ US$0.5758 33.6% of flow Common Stock SEC:0000899243-23-010715:0
▲ Chief Financial Officer · Executives · 24 May 2022
9,500 shares @ US$1.12 0.076% mcap 100.0% of flow Common Stock SEC:0000899243-22-019461:0
Canonical exit: 22 Aug 2022 (T+90) ▼ Chief Operating Officer · Executives · 4 Apr 2022
2,650 shares @ US$2.4459 0.045% mcap 100.0% of flow Common Stock SEC:0000899243-22-014109:0
▼ See Remarks · Executives · 4 Apr 2022
8,894 shares @ US$2.4459 0.15% mcap 100.0% of flow Common Stock SEC:0000899243-22-014110:0
◆ Chief Financial Officer · Executives · 3 Mar 2022
30,000 shares 0Common Stock SEC:0000899243-22-009122:0
◆ Chief Operating Officer · Executives · 4 Feb 2022
40,820 shares 0Common Stock SEC:0000899243-22-005207:0
◆ See Remarks · Executives · 4 Feb 2022
106,920 shares 0Common Stock SEC:0000899243-22-005213:0
关于 Synlogic, INC. Synlogic, Inc. 是一家在美国上市的生物制药公司,在纳斯达克资本市场交易,使其完全处于纳斯达克体系和美国市场中。从国际股权角度来看,Synlogic 应被视为一家处于开发阶段的生物技术公司,而非成熟的商业制药平台。该公司于2014年在马萨诸塞州剑桥成立,其历史运营基地位于波士顿/剑桥生物技术集群。然而,其2024年的报告显示,该公司终止了其前剑桥总部的租约,并将其官方总部地址迁至马萨诸塞州温彻斯特,同时进行了一次广泛的重组。([sec.gov](https://www.sec.gov/Archives/edgar/data/1527599/000156459020023231/R7.htm?utm_source=openai))
Synlogic 的商业模式一直以专有的合成生物学和微生物组平台为中心。该公司一直在开发口服、非全身吸收的治疗候选药物,称为“合成益生菌”,旨在肠道中发挥作用,提供靶向代谢或治疗效果。历史上,其项目一直专注于高度未满足需求的领域,例如先天性代谢缺陷、高氨血症、苯丙酮尿症和选定的炎症疾病。实际上,Synlogic 的价值主张一直与平台验证、临床概念验证、监管进展和潜在战略合作伙伴关系相关联,而非广泛的市场产品组合。([investor.synlogictx.com](https://investor.synlogictx.com/news-releases/news-release-details/synlogic-reports-fourth-quarter-and-full-year-2017-financial?utm_source=openai))
竞争定位仍然充满挑战。Synlogic 在一个拥挤的生物技术领域运营,与在重叠适应症中采用酶替代、基因、微生物组和传统药物方法的公司竞争。该公司的备案文件强调,竞争对手可能会更快或更成功地发现、开发或商业化产品。因此,Synlogic 具有比多元化运营业务更不对称、更二元化的特征:投资案例在很大程度上取决于少数开发项目以及公司通过战略交易或融资事件保值的能力。([sec.gov](https://www.sec.gov/Archives/edgar/data/1527599/000095017025034820/sybx-20241231.htm?utm_source=openai))
最近的发展尤为重要。2024年,Synlogic 完成了一次重大的公司重组,包括重大的重组费用和退出其剑桥总部。2025年,该公司继续审查战略替代方案,纳斯达克告知 Synlogic,它认为该公司是一个“公共空壳”,对其证券的持续上市提出了质疑。对于投资者而言,这是一个重要的危险信号:它表明运营范围高度受限,上市股权的不确定性升高,以及这种情况更多地关乎资产负债表保全和战略选择权,而非近期商业规模化。([sec.gov](https://www.sec.gov/Archives/edgar/data/1527599/000095017025034820/sybx-20241231.htm?utm_source=openai))