Revolution Medicines, Inc. Stock: price and directors' dealings · United States · SEC (Form 4)Track the Revolution Medicines, Inc. stock price and the full management transaction log of the company, a listed issuer based in United States. Shares trade on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Revolution Medicines, Inc. has recorded 331 public disclosures. The latest transaction was disclosed on 31 August 2026 (Notice of proposed sale (Form 144)). Among the most active insiders: GOLDSMITH MARK A. All data is free.
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Last declaration on 31 August 2026
All Executives331 Thresholds0 Prospectus0 Other0
Declarations 331 total
● Affiliate · Executives · 31 Aug 2026
73,090 shares @ US$207.88 Common SEC144:0001968582-26-000898
▼ See Remarks · Executives · 21 Aug 2026
24,917 shares @ US$208.3697 11.3% of flow Common Stock SEC:0001610717-26-000387:2
◇ General Counsel · Executives · 21 Aug 2026
26,600 shares @ US$21.61 3.4% of flow Common Stock SEC:0001610717-26-000388:1
▼ General Counsel · Executives · 21 Aug 2026
3,314 shares @ US$212.0583 4.2% of flow Common Stock SEC:0001610717-26-000388:7
▼ See Remarks · Executives · 21 Aug 2026
1,351 shares @ US$209.2812 0.6% of flow Common Stock SEC:0001610717-26-000387:9
▼ See Remarks · Executives · 21 Aug 2026
126 shares @ US$210.403 0.1% of flow Common Stock SEC:0001610717-26-000387:16
▼ See Remarks · Executives · 21 Aug 2026
1,405 shares @ US$209.2664 0.6% of flow Common Stock SEC:0001610717-26-000387:15
◇ General Counsel · Executives · 21 Aug 2026
29,680 shares @ US$18.56 3.3% of flow Common Stock SEC:0001610717-26-000388:0
▼ General Counsel · Executives · 21 Aug 2026
3,400 shares @ US$207.2363 4.2% of flow Common Stock SEC:0001610717-26-000388:2
▼ General Counsel · Executives · 21 Aug 2026
17,323 shares @ US$208.3688 21.5% of flow Common Stock SEC:0001610717-26-000388:3
▼ General Counsel · Executives · 21 Aug 2026
25,817 shares @ US$209.2497 32.2% of flow Common Stock SEC:0001610717-26-000388:4
▼ General Counsel · Executives · 21 Aug 2026
2,540 shares @ US$210.2647 3.2% of flow Common Stock SEC:0001610717-26-000388:5
▼ General Counsel · Executives · 21 Aug 2026
4,500 shares @ US$211.3417 5.7% of flow Common Stock SEC:0001610717-26-000388:6
◇ See Remarks · Executives · 21 Aug 2026
80,000 shares @ US$4.73 0.8% of flow Common Stock SEC:0001610717-26-000387:0
▼ See Remarks · Executives · 21 Aug 2026
5,128 shares @ US$207.233 2.3% of flow Common Stock SEC:0001610717-26-000387:1
▼ See Remarks · Executives · 21 Aug 2026
35,938 shares @ US$209.2615 16.3% of flow Common Stock SEC:0001610717-26-000387:3
▼ See Remarks · Executives · 21 Aug 2026
3,813 shares @ US$210.2466 1.7% of flow Common Stock SEC:0001610717-26-000387:4
▼ See Remarks · Executives · 21 Aug 2026
6,583 shares @ US$211.3331 3.0% of flow Common Stock SEC:0001610717-26-000387:5
▼ See Remarks · Executives · 21 Aug 2026
3,621 shares @ US$212.0776 1.7% of flow Common Stock SEC:0001610717-26-000387:6
▼ See Remarks · Executives · 21 Aug 2026
190 shares @ US$207.2454 0.1% of flow Common Stock SEC:0001610717-26-000387:7
▼ See Remarks · Executives · 21 Aug 2026
951 shares @ US$208.3648 0.4% of flow Common Stock SEC:0001610717-26-000387:8
▼ See Remarks · Executives · 21 Aug 2026
136 shares @ US$210.4017 0.1% of flow Common Stock SEC:0001610717-26-000387:10
▼ See Remarks · Executives · 21 Aug 2026
245 shares @ US$211.4651 0.1% of flow Common Stock SEC:0001610717-26-000387:11
▼ See Remarks · Executives · 21 Aug 2026
127 shares @ US$212.0635 0.1% of flow Common Stock SEC:0001610717-26-000387:12
▼ See Remarks · Executives · 21 Aug 2026
177 shares @ US$207.2515 0.1% of flow Common Stock SEC:0001610717-26-000387:13
25 of 331 declarations
Load more (306 remaining) 关于 Revolution Medicines, Inc. Revolution Medicines, Inc. 是一家在美国纳斯达克市场上市的美国生物制药公司,总部位于美国加利福尼亚州雷德伍德城。对于国际投资者而言,该公司代表了一个专注于精准肿瘤学的案例,而非一个广泛的商业制药平台。其核心战略是开发针对所谓RAS成瘾性癌症的疗法,即那些生长由致癌RAS通路突变驱动的肿瘤。这种科学重点使Revolution Medicines处于生物技术领域一个专业化、研究密集型的细分市场,其估值主要由临床执行和数据质量决定。
该公司成立于2014年,在过去的几年里,围绕抑制RAS生物学这一长期挑战,建立了一条产品管线。其项目集中于RAS(ON)抑制剂,旨在靶向活性RAS蛋白和特定的致癌变体。主要候选药物是daraxonrasib (RMC-6236),一种多选择性RAS(ON)抑制剂。其他主要资产包括elironrasib (RMC-6291),一种G12C选择性抑制剂;zoldonrasib (RMC-9805),一种G12D选择性抑制剂;以及RMC-5127,一种G12V选择性抑制剂。该公司还在其他RAS突变背景下寻求额外机会,包括Q61H和G13C。
从竞争角度来看,Revolution Medicines之所以脱颖而出,是因为它试图解决肿瘤学领域最具商业和医学重要性的通路之一中的多个突变热点。其机会集中在胰腺癌和某些肺癌人群等高度未满足需求的癌症中。因此,投资案例高度受催化剂驱动:公司的发展轨迹取决于临床数据、反应持久性、安全性/耐受性、监管参与,以及最终将早期信号转化为可批准的差异化疗法的能力。
近期进展进一步强化了这一特点。2026年4月,Revolution Medicines报告了daraxonrasib在一线转移性胰腺癌中的更新的1/2期数据,并强调了在既往治疗的转移性胰腺癌中取得的积极的3期RASolute 302关键性结果。该公司还在2026年4月通过增发普通股和可转换票据完成了大规模融资,突显了晚期肿瘤开发典型的资金密集度。2026年5月,该公司报告了2026年第一季度财务业绩,并继续强调其RAS(ON)产品管线的进展。