iTeos Therapeutics, Inc. Stock: price and insider trades · United States · SEC (Form 4)Track the iTeos Therapeutics, Inc. share price and the full insider trade history of the company, a listed issuer based in United States. Shares are quoted on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, iTeos Therapeutics, Inc. has published 108 reports. The latest transaction was filed on 16 May 2025 (Acquisition). Among the most active insiders: MPM BioVentures 2014, L.P.. The full history is accessible without an account.
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Last declaration on 16 May 2025
All Executives108 Thresholds0 Prospectus0 Other0
Declarations 108 total
1,658,978 shares @ US$7.4055 100.0% of flow Common Stock SEC:0000935836-25-000384:0
Canonical exit: 12 Aug 2025 (T+90) 630,191 shares @ US$8.06 20.0% of flow Common Stock SEC:0001415889-25-013248:0
1,031,931 shares @ US$8.06 19.7% of flow Common Stock SEC:0001415889-25-013252:0
630,191 shares @ US$8.06 20.0% of flow Common Stock SEC:0001415889-25-013251:0
◇ Director · Executives · 13 May 2025
22,346 shares @ US$4.30 100.0% of flow Common Stock SEC:0000950170-25-071755:0
◆ Chief Scientific Officer · Executives · 7 Mar 2025
15,300 shares 0Common Stock SEC:0000950170-25-037513:0
◆ Chief Executive Officer · Executives · 7 Mar 2025
77,000 shares 0Common Stock SEC:0000950170-25-037515:0
◆ Chief Operating Officer · Executives · 7 Mar 2025
24,000 shares 0Common Stock SEC:0000950170-25-037520:0
◆ Chief Financial Officer · Executives · 7 Mar 2025
24,000 shares 0Common Stock SEC:0000950170-25-037512:0
◆ Chief Medical Officer · Executives · 6 Dec 2024
47,000 shares 0Common Stock SEC:0000950170-24-134239:0
▲ Chief Financial Officer · Executives · 19 Nov 2024
5,000 shares @ US$7.727 4.3% of flow Common Stock SEC:0000950170-24-128956:0
Canonical exit: 17 Feb 2025 (T+90) 900,000 shares Common Stock SEC:0001415889-24-013171:0
1,142,857 shares @ US$17.50 25.2% of flow Common Stock SEC:0000895345-24-000172:0
◆ Chief Financial Officer · Executives · 5 Dec 2023
41,000 shares 0Common Stock SEC:0000950170-23-068901:0
◆ Chief Executive Officer · Executives · 5 Dec 2023
30,000 shares 0Common Stock SEC:0000950170-23-068900:0
◆ Chief Scientific Officer · Executives · 5 Dec 2023
31,000 shares 0Common Stock SEC:0000950170-23-068903:0
◆ Chief Operating Officer · Executives · 5 Dec 2023
44,000 shares 0Common Stock SEC:0000950170-23-068902:0
▲ Chief Financial Officer · Executives · 12 Oct 2023
5,000 shares @ US$8.37 4.6% of flow Common Stock SEC:0001209191-23-052709:0
Canonical exit: 10 Jan 2024 (T+90) 34,846 shares @ US$14.19 0.6% of flow Common Stock SEC:0000895345-23-000524:0
◇ Chief Operating Officer · Executives · 28 Mar 2023
40,226 shares @ US$2.95 29.1% of flow Common Stock SEC:0001209191-23-021566:0
◇ Director · Executives · 8 Jun 2022
5,968 shares @ US$4.23 13.3% of flow Common Stock SEC:0001209191-22-036137:0
▼ Director · Executives · 9 May 2022
25,000 shares @ US$22.9089 10.7% of flow Common Stock SEC:0000899243-22-017712:0
▼ Director · Executives · 28 Apr 2022
150,000 shares @ US$27.4021 77.2% of flow Common Stock SEC:0000899243-22-016203:0
◇ Chief Executive Officer · Executives · 18 Apr 2022
11,500 shares @ US$4.23 1.0% of flow Common Stock SEC:0001209191-22-024859:0
▲ Director · Executives · 22 Mar 2022
21,300 shares @ US$31.875 12.2% of flow Common Stock SEC:0000899243-22-012152:0
Canonical exit: 20 Jun 2022 (T+90) 25 of 108 declarations
Load more (83 remaining) 关于 iTeos Therapeutics, Inc. iTeos Therapeutics, Inc. 是一家在美国纳斯达克上市的美国生物制药公司,专注于免疫肿瘤学。公司总部位于马萨诸塞州沃特敦,在比利时戈瑟利斯设有一个研究中心。其根源可追溯到2011年在比利时成立的生物技术平台,而当前的特拉华州注册母公司 iTeos Therapeutics, Inc. 则于2019年作为美国继承结构成立。iTeos 作为一家临床阶段的肿瘤公司运营,其产品组合以单克隆抗体和小分子为中心,旨在解决经过验证的免疫途径,尤其是在实体瘤方面。
公司主要资产是 belrestotug,一种抗 TIGIT 抗体,旨在对抗肿瘤诱导的免疫抑制并增强抗肿瘤免疫活性。iTeos 与葛兰素史克 (GSK) 合作开发了该项目,根据全球合作和许可协议,GSK 拥有美国以外的商业化权利,而 iTeos 和 GSK 共同承担开发责任和美国商业权利。这种伙伴关系一直是 iTeos 的关键战略资产,提供了科学验证、成本分摊和重要的里程碑潜力。更广泛的管线还包括腺苷途径项目,例如 inupadenant (EOS-850),尽管该公司在2024年表示中期数据不足以在该阶段进行进一步投资。
从竞争角度来看,iTeos 活跃于肿瘤药物开发中最拥挤和科学要求最高的领域之一。成功取决于临床差异化、生物标志物策略、合作伙伴质量和资本效率。公司的主要优势在于其转化肿瘤免疫学专业知识、跨国美比运营模式以及与大型制药合作伙伴合作的能力。同时,其业务概况仍是晚期生物技术公司的典型特征:管线风险集中、研发投入高以及在产品商业化之前收入可见性有限。与葛兰素史克的联盟在将 iTeos 定位为一家可靠的免疫肿瘤开发商而非纯粹的临床前公司方面发挥了核心作用。
从地理上看,iTeos 保持着跨大西洋的足迹,在美国和比利时都拥有运营能力。最近的一项重大进展是2025年7月宣布的最终协议,Concentra Biosciences 将以每股10.047美元现金加或有价值权的方式收购 iTeos,此前 iTeos 进行了战略审查并获得了董事会批准。对于投资者而言,这意味着 iTeos 应被视为具有显著战略选择权的生物技术资产,但也是一家其股权故事现在与交易结果而非仅仅是独立管线执行密切相关的公司。