Horizon Therapeutics Public Ltd Co Stock: price and insider trades · United States · SEC (Form 4)Track the Horizon Therapeutics Public Ltd Co stock price and the full directors' dealings record of the company, a listed issuer based in United States. Shares are listed on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Horizon Therapeutics Public Ltd Co has published 139 insider filings. The latest transaction was disclosed on 6 October 2023 (Disposition). Among the most active insiders: Walbert Timothy P. All data is free.
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Last declaration on 6 October 2023
All Executives139 Thresholds0 Prospectus0 Other0
Declarations 139 total
● EVP, General Counsel · Executives · 6 Oct 2023
7,655 shares @ US$116.50 94.6% of flow Ordinary Shares SEC:0001209191-23-052359:0
● Director · Executives · 6 Oct 2023
25,672 shares @ US$116.50 100.0% of flow Ordinary Shares SEC:0001209191-23-052374:0
● Director · Executives · 6 Oct 2023
31,915 shares @ US$116.50 89.4% of flow Ordinary Shares SEC:0001209191-23-052372:0
● EVP and Chief Medical Officer · Executives · 6 Oct 2023
2,655 shares @ US$116.50 5.8% of flow Ordinary Shares SEC:0001209191-23-052358:0
● EVP, Chief Strategy Officer · Executives · 6 Oct 2023
56,338 shares @ US$116.50 48.1% of flow Ordinary Shares SEC:0001209191-23-052364:0
● Director · Executives · 6 Oct 2023
100,959 shares @ US$116.50 94.6% of flow Ordinary Shares SEC:0001209191-23-052367:0
● EVP, Research & Development · Executives · 6 Oct 2023
14,575 shares @ US$116.50 41.9% of flow Ordinary Shares SEC:0001209191-23-052363:0
● Director · Executives · 6 Oct 2023
39,361 shares @ US$116.50 93.1% of flow Ordinary Shares SEC:0001209191-23-052373:0
● EVP, Chief Financial Officer · Executives · 6 Oct 2023
556 shares @ US$116.50 1.6% of flow Ordinary Shares SEC:0001209191-23-052362:0
● Director · Executives · 6 Oct 2023
110,447 shares @ US$116.50 96.3% of flow Ordinary Shares SEC:0001209191-23-052376:0
● Chairman, President and CEO · Executives · 6 Oct 2023
616,772 shares @ US$116.50 76.4% of flow Ordinary Shares SEC:0001209191-23-052361:0
● Director · Executives · 6 Oct 2023
44,546 shares @ US$116.50 92.1% of flow Ordinary Shares SEC:0001209191-23-052371:0
● Director · Executives · 6 Oct 2023
9,345 shares @ US$116.50 100.0% of flow Ordinary Shares SEC:0001209191-23-052375:0
● EVP, Technical Operations · Executives · 6 Oct 2023
126,838 shares @ US$116.50 83.0% of flow Ordinary Shares SEC:0001209191-23-052360:0
● Director · Executives · 6 Oct 2023
33,156 shares @ US$116.50 96.4% of flow Ordinary Shares SEC:0001209191-23-052370:0
● Chief Accounting Officer · Executives · 6 Oct 2023
6,874 shares @ US$116.50 100.0% of flow Ordinary Shares SEC:0001209191-23-052366:0
◇ Director · Executives · 29 Sept 2023
40,000 shares @ US$12.29 3.7% of flow Ordinary Shares SEC:0001209191-23-051234:0
◇ Director · Executives · 29 Sept 2023
11,850 shares @ US$12.19 3.6% of flow Ordinary Shares SEC:0001209191-23-051231:0
◇ Director · Executives · 2 Oct 2023
23,092 shares @ US$15.23 2.8% of flow Ordinary Shares SEC:0001209191-23-051236:0
◇ Director · Executives · 28 Sept 2023
20,000 shares @ US$15.96 6.5% of flow Ordinary Shares SEC:0001209191-23-050737:0
◇ Director · Executives · 26 Sept 2023
32,161 shares @ US$13.87 7.9% of flow Ordinary Shares SEC:0001209191-23-050674:0
◇ Director · Executives · 22 Sept 2023
20,000 shares @ US$15.96 2.5% of flow Ordinary Shares SEC:0001209191-23-050519:0
● EVP and Chief Medical Officer · Executives · 6 Sept 2023
2,165 shares 0Ordinary Shares SEC:0001209191-23-048609:0
● Director · Executives · 9 May 2023
7,873 shares 0Ordinary Shares SEC:0001209191-23-028795:0
◇ Director · Executives · 28 Apr 2023
3,913 shares Ordinary Shares SEC:0001209191-23-026754:0
25 of 139 declarations
Load more (114 remaining) 关于 Horizon Therapeutics Public Ltd Co Horizon Therapeutics Public Ltd Co(股票代码 HZNP)是一家专注于美国市场的生物制药公司,在美国纳斯达克上市,围绕罕见病、自身免疫性疾病和严重炎症性疾病的专科药物而建立。该公司于2005年在伊利诺伊州成立,后来通过税收倒置将其法定总部迁至爱尔兰,但其商业足迹和收入基础仍高度集中在美国。对于投资者而言,Horizon 最好被理解为一个高度集中的专科制药平台,而非一个广泛多元化的制药集团。
其商业模式的核心是发现、开发和商业化针对医疗服务不足患者群体的药物。Horizon 的核心商业特许经营权包括用于甲状腺眼病的 TEPEZZA、用于慢性难治性痛风的 KRYSTEXXA 以及用于某些罕见自身免疫适应症的 UPLIZNA。其产品组合还包括 RAVICTI、PROCYSBI、ACTIMMUNE、PENNSAID 2% 和 DUEXIS,反映了增长型资产和成熟专科产品的组合。在其2022年年度报告中,Horizon 将自己描述为一家全球生物技术公司,致力于解决罕见病、自身免疫性疾病和严重炎症性疾病中的关键需求,其产品组合具有重要的国际性,尽管其业务仍主要由美国驱动。
从竞争角度来看,Horizon 的优势来自于其在专科商业化方面的深厚专业知识:接触疾病专家、提高医生认知、支持患者识别和依从性,以及通过临床数据生成扩大适应症。这种模式赋予了 Horizon 比许多小型生物技术公司更强的护城河,因为其产品针对的是狭窄、未满足需求高的市场,在这些市场中,执行力和临床差异化比大众市场规模更为重要。与此同时,该公司也面临集中风险,因为有限数量的分子占据了其大部分增长和投资者关注。在其被收购之前,TEPEZZA、KRYSTEXXA 和 UPLIZNA 是主要的收入驱动因素和平台实力的最清晰指标。
最近最重要的公司事件是 Amgen 宣布并完成了对 Horizon 的收购,于2023年10月6日完成,现金对价约为 $27.8 billion。因此,Horizon 不再是一家独立交易的公司,SEC Form 4 文件中对 HZNP 的引用主要是交易完成前的历史内部人交易记录。从战略角度来看,Horizon 成为了一个显著的罕见病成功案例,通过专科产品商业化创造了巨大的价值,随后被一家更大的美国制药公司吸收。([sec.gov](https://www.sec.gov/Archives/edgar/data/1492426/000095017023005337/hznp-20221231.htm?utm_source=openai))