Axsome Therapeutics, Inc. Stock: price and management transactions · United States · SEC (Form 4)Follow the Axsome Therapeutics, Inc. stock price and the full management transaction log of the company, a listed issuer based in United States. Shares trade on the US market, under the authority of SEC (Form 4). Operating in the Healthcare & Pharma sector, Axsome Therapeutics, Inc. has logged 99 public disclosures. Market capitalisation: €10.4bn. The latest transaction was reported on 3 September 2026 (Levée d'options). Among the most active insiders: Coleman Mark. The full history is openly available.
Analyst consensus: bullish or bearish? Analysts rate Axsome Therapeutics, Inc. Strong Buy (bullish), based on 21 analysts. Average price target: US$285.42.
This score ranks the purchase within its own market. No market currently meets the historical allocation criteria, so signals remain watch-only. Not investment advice.
Fundamental score
Ranked 22,593 of 29,063 companies
FCF yld -0.9%
Earn yld -1.8%
EV/EBITDA ·
ROE -245%
Gross mgn 93%
Net mgn -29%
Debt/EBITDA ·
Pillars 2/3
Transparent value + quality ranking, distinct from the insider signal.
Σ Sigma AI Analysis Fundamental view, insider signal, bull and bear case, synthesis.
AI analysis generation is paused.
Last declaration on 3 September 2026
All Executives99 Thresholds0 Prospectus0 Other0
Declarations 99 total
◇ Chief Operating Officer · Executives · 3 Sept 2026
10,000 shares @ US$12.95 0.0012% mcap 1.1% of flow Common Stock SEC:0001193125-26-382277:0
▼ Chief Operating Officer · Executives · 3 Sept 2026
10,000 shares @ US$208.65 0.020% mcap 17.4% of flow Common Stock SEC:0001193125-26-382277:1
● Officer · Executives · 3 Sept 2026
10,000 shares @ US$208.35 Class A Common SEC144:0001958244-26-000571
◇ Chief Executive Officer · Executives · 5 Aug 2026
45,004 shares @ US$4.95 0.0020% mcap 1.1% of flow Common Stock SEC:0001193125-26-340688:0
▼ Chief Executive Officer · Executives · 5 Aug 2026
45,004 shares @ US$212.01 0.087% mcap 46.2% of flow Common Stock SEC:0001193125-26-340688:1
◇ Chief Executive Officer · Executives · 6 Aug 2026
4,660 shares @ US$4.95 0.0002% mcap 0.1% of flow Common Stock SEC:0001193125-26-340688:2
▼ Chief Executive Officer · Executives · 6 Aug 2026
4,660 shares @ US$213.95 0.0091% mcap 4.8% of flow Common Stock SEC:0001193125-26-340688:3
● Officer · Executives · 6 Aug 2026
4,660 shares @ US$210.13 0.0089% mcap 2.8% of flow Common Stock SEC144:0001958244-26-000491
● Officer · Executives · 5 Aug 2026
45,004 shares @ US$212.85 0.088% mcap 28.3% of flow Common Stock SEC144:0001958244-26-000488
● Officer · Executives · 1 Jul 2026
49,666 shares @ US$240.66 0.094% mcap 100.0% of flow Common Stock SEC144:0001958244-26-000417
◇ Chief Executive Officer · Executives · 1 Jul 2026
49,666 shares Common Stock SEC:0001193125-26-292985:0
▼ Chief Executive Officer · Executives · 1 Jul 2026
49,666 shares Common Stock SEC:0001193125-26-292985:1
● Director · Executives · 11 Jun 2026
286 shares @ US$249.1189 0.0006% mcap 0.8% of flow Common SEC144:0001921094-26-000636
▼ Director · Executives · 10 Jun 2026
286 shares Common Stock SEC:0001193125-26-268202:0
▼ Director · Executives · 11 Jun 2026
286 shares Common Stock SEC:0001193125-26-268202:1
● Director · Executives · 10 Jun 2026
643 shares @ US$249.0031 0.0013% mcap 1.5% of flow Common SEC144:0001921094-26-000631
● Director · Executives · 10 Jun 2026
286 shares @ US$246.1783 0.0006% mcap 0.8% of flow Common SEC144:0001921094-26-000632
● Director · Executives · 10 Jun 2026
300 shares @ US$246.18 0.0006% mcap 50.9% of flow Common SEC144:0001921094-26-000633
◇ Director · Executives · 8 Jun 2026
1,429 shares Common Stock SEC:0001193125-26-266433:0
▼ Director · Executives · 10 Jun 2026
643 shares Common Stock SEC:0001193125-26-266433:1
◇ Director · Executives · 8 Jun 2026
1,429 shares Common Stock SEC:0001193125-26-266435:0
▼ Director · Executives · 9 Jun 2026
300 shares Common Stock SEC:0001193125-26-266435:1
▼ Director · Executives · 10 Jun 2026
300 shares Common Stock SEC:0001193125-26-266435:2
◇ Director · Executives · 8 Jun 2026
1,429 shares Common Stock SEC:0001193125-26-266436:0
◇ Director · Executives · 8 Jun 2026
1,429 shares Common Stock SEC:0001193125-26-266437:0
25 of 99 declarations
Load more (74 remaining) 关于 Axsome Therapeutics, Inc. Axsome Therapeutics, Inc. 是一家总部位于美国的生物制药公司,专注于中枢神经系统 (CNS) 疾病。由于持续未满足的医疗需求,该治疗领域既具有临床挑战性,又具有商业吸引力。Axsome 成立于 2012 年,其战略围绕开发和商业化针对精神和神经疾病的差异化疗法。该公司在纳斯达克上市,股票代码为 AXSM,公司总部位于美国纽约。([stockanalysis.com](https://stockanalysis.com/stocks/axsm/company/?utm_source=openai))
Axsome 的商业模式现在将已上市产品与处于后期阶段的 CNS 产品线相结合。其核心商业资产包括获批用于成人重度抑郁症的 AUVELITY;用于治疗与发作性睡病或阻塞性睡眠呼吸暂停相关的过度嗜睡的 SUNOSI;以及 SYMBRAVO,该产品于 2025 年 1 月获得 FDA 批准,用于成人有或无先兆偏头痛的急性治疗。该公司还强调其用于特定配方的专有 MoSEIC 技术,并将其产品组合定位为旨在解决复杂 CNS 症状的多机制方法。([stockanalysis.com](https://stockanalysis.com/stocks/axsm/company/?utm_source=openai))
从竞争角度来看,Axsome 在竞争激烈的市场中运营,这些市场由大型制药公司以及专注于神经科学的专业公司主导。其差异化在于产品创新、临床执行以及其已上市产品组合的逐步扩张。Axsome 将自己描述为针对现有选择有限的疾病中的治疗空白,如果医生采纳率和支付方可及性持续改善,这可以支持其高端定位。([axsome.com](https://www.axsome.com/about-axsome/))
从地理上看,该公司主要以美国为中心。其商业足迹、收入产生和主要的监管互动主要与美国相关,尽管一些 SEC 文件提及与非美国权利或结构相关的实体和协议。对于投资者而言,实际运营基础仍然绝大多数在美国。([sec.gov](https://www.sec.gov/Archives/edgar/data/1579428/000095017025058788/axsm_fy2024_ars.pdf))
近期发展对投资案例很重要。2025 年 1 月,FDA 批准了 SYMBRAVO,Axsome 表示正在准备于 2025 年 6 月开始商业发布。该公司还在阿尔茨海默病激越的 AXS-05 方面取得了进展,包括在 2025 年 3 月与 FDA 进行了积极的 NDA 前互动,并计划提交补充 NDA。与此同时,Axsome 继续扩大其销售团队并加强围绕 AUVELITY 和 SUNOSI 的商业基础设施。总而言之,这些里程碑巩固了 Axsome 作为一家纳斯达克上市的美国神经科学成长型公司的形象,该公司正在从以开发为主的执行向更加多元化的商业平台转型。([axsometherapeuticsinc.gcs-web.com](https://axsometherapeuticsinc.gcs-web.com/node/12031/pdf))