Arbutus Biopharma Corp Stock: price and management transactions · United States · SEC (Form 4)Follow the Arbutus Biopharma Corp share price and the full insider trade history of the company, a listed equity based in United States. Shares are quoted on the US market, under the oversight of SEC (Form 4). Operating in the Healthcare & Pharma sector, Arbutus Biopharma Corp has recorded 23 public disclosures. Market capitalisation: €892.9m. The latest transaction was disclosed on 2 February 2026 (Attribution). Among the most active insiders: McElhaugh Michael J.. Every trade is openly available.
Analyst consensus: bullish or bearish? Analysts rate Arbutus Biopharma Corp Strong Buy (bullish), based on 2 analysts. Average price target: US$5.16.
This score ranks the purchase within its own market. No market currently meets the historical allocation criteria, so signals remain watch-only. Not investment advice.
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Last declaration on 2 February 2026
All Executives23 Thresholds0 Prospectus0 Other0
Declarations 23 total
◆ Chief Financial Officer · Executives · 2 Feb 2026
73,500 shares 0Common Shares SEC:0001447028-26-000009:0
◆ President and CEO · Executives · 2 Feb 2026
28,000 shares 0Common Shares SEC:0001447028-26-000008:0
◆ Interim President & CEO · Executives · 14 Feb 2025
177,000 shares 0Common Shares SEC:0001447028-25-000051:0
◆ Chief Medical Officer · Executives · 14 Feb 2025
49,300 shares 0Common Shares SEC:0001447028-25-000049:0
◆ Chief Financial Officer · Executives · 14 Feb 2025
90,100 shares 0Common Shares SEC:0001447028-25-000050:0
◆ General Counsel and CCO · Executives · 14 Feb 2025
54,300 shares 0Common Shares SEC:0001447028-25-000052:0
▼ Interim President & CEO · Executives · 4 Feb 2025
23,790 shares @ US$3.283 100.0% of flow Common Shares SEC:0001447028-25-000038:0
▼ Chief Financial Officer · Executives · 4 Feb 2025
22,183 shares @ US$3.283 100.0% of flow Common Shares SEC:0001447028-25-000040:0
▼ General Counsel and CCO · Executives · 4 Feb 2025
11,333 shares @ US$3.283 100.0% of flow Common Shares SEC:0001447028-25-000037:0
▼ Chief Medical Officer · Executives · 4 Feb 2025
19,348 shares @ US$3.283 100.0% of flow Common Shares SEC:0001447028-25-000039:0
◇ Director · Executives · 14 Aug 2024
54,915 shares @ US$0.56 100.0% of flow Common Shares SEC:0001447028-24-000078:0
◆ General Counsel and CCO · Executives · 1 Feb 2024
95,100 shares 0Common Shares SEC:0001447028-24-000029:0
◆ Chief Scientific Officer · Executives · 1 Feb 2024
109,500 shares 0Common Shares SEC:0001447028-24-000026:0
◆ Interim President & CEO · Executives · 1 Feb 2024
123,800 shares 0Common Shares SEC:0001447028-24-000025:0
◆ Chief Medical Officer · Executives · 1 Feb 2024
101,000 shares 0Common Shares SEC:0001447028-24-000028:0
◆ Chief Financial Officer · Executives · 1 Feb 2024
112,500 shares 0Common Shares SEC:0001447028-24-000027:0
◆ Chief Financial Officer · Executives · 1 Feb 2023
79,000 shares 0Common Shares SEC:0001447028-23-000009:0
◆ Chief Business Officer · Executives · 1 Feb 2023
83,700 shares 0Common Shares SEC:0001447028-23-000011:0
◆ President and CEO · Executives · 1 Feb 2023
216,500 shares 0Common Shares SEC:0001447028-23-000008:0
◆ Chief Scientific Officer · Executives · 1 Feb 2023
82,200 shares 0Common Shares SEC:0001447028-23-000010:0
◆ EVP, GC, Compliance · Executives · 1 Feb 2023
69,700 shares 0Common Shares SEC:0001447028-23-000007:0
▼ Chief Scientific Officer · Executives · 1 Dec 2021
200,000 shares @ US$5.09 0.11% mcap 50.0% of flow Common Shares SEC:0001447028-21-000068:0
22,833,922 shares Common shares, without par value SEC:0000950103-21-016172:0
关于 Arbutus Biopharma Corp Arbutus Biopharma Corp.(股票代码:ABUS)是一家在美国纳斯达克市场交易的美国上市临床阶段生物制药公司。对于投资者而言,它代表了一个专注于病毒学的生物技术公司,而非多元化的制药平台:该公司以慢性乙型肝炎(HBV)为核心治疗重点。Arbutus 总部位于宾夕法尼亚州沃明斯特,其身份围绕抗病毒药物开发和递送技术,特别是脂质纳米颗粒(LNP)科学,这已成为该公司日益重要的战略资产。([arbutusbio.com](https://www.arbutusbio.com/))
该公司的历史可追溯到 Tekmira Pharmaceuticals,该公司于 2015 年更名为 Arbutus Biopharma,同时将其重点放在寻找慢性乙型肝炎的解决方案上。这一转变不仅仅是表面上的:它反映了战略上向 HBV 以及旨在通过多种机制攻击病毒的联合治疗方案的收窄。Arbutus 现在通过“抑制、减少、增强”的方法来制定其开发策略,旨在协调一致地阻断病毒复制、减少病毒抗原并刺激宿主免疫反应。([arbutusbio.gcs-web.com](https://arbutusbio.gcs-web.com/news-releases/news-release-details/tekmira-announces-launch-arbutus-biopharma-hepatitis-b-solutions?utm_source=openai))
该公司的主要临床资产是 imdusiran,一种针对慢性 HBV 的 RNAi 疗法。Arbutus 还在早期临床试验中推进 AB-101,一种口服 PD-L1 抑制剂。在最近的公司更新中,管理层强调了 imdusiran 在 2a 期研究中令人鼓舞的功能性治愈信号,以及 AB-101 良好的早期安全性和受体占有率数据。这使得 ABUS 具有经典的临床生物技术特征:如果数据持续改善,则有很高的上行空间,但如果临床反应停滞或安全性/耐受性成为问题,则存在重大的执行和开发风险。([arbutusbio.gcs-web.com](https://arbutusbio.gcs-web.com/news-releases/news-release-details/arbutus-reports-first-quarter-2025-financial-results-and))
投资案例的第二个主要支柱是知识产权。Arbutus 拥有有价值的 LNP 相关专利和技术,这些资产一直是其诉讼和许可经济的核心。2026 年,该公司宣布与 Moderna 达成全球和解,涉及与 LNP 递送技术相关的专利侵权指控,预计今年晚些时候将获得大笔前期付款。该和解协议实质性改善了 Arbutus 的财务状况,并可能支持资本回报讨论,同时该公司还通过 Genevant 继续支持涉及 Pfizer/BioNTech 的相关法律工作。([investor.arbutusbio.com](https://investor.arbutusbio.com/news-releases/news-release-details/arbutus-reports-fourth-quarter-and-year-end-2025-financial))
从地理上看,Arbutus 的运营足迹以美国为基础,总部设在宾夕法尼亚州,但其商业相关性是全球性的,因为慢性乙型肝炎是一种全球性疾病领域,而且其技术和专利纠纷对更广泛的核酸递送生态系统具有影响。简而言之,ABUS 是一家在美国纳斯达克上市的专业传染病生物技术公司,其以管线为主导的故事辅以可变现的知识产权和重大的法律催化剂。([arbutusbio.com](https://www.arbutusbio.com/))