Every trade that managers of Vaxcyte, Inc. disclose to SEC (Form 4) is tracked on this page. The company sits in the Healthcare & Pharma sector. From 18 October 2025 to 18 October 2026, the disclosure feed for Vaxcyte, Inc. logged 75 filings by 15 insiders.
There is no open-market purchase to report; the filings show 27 sales worth €4.0M by 5 insiders. The totals exclude 1 filing filed without an amount. The largest single trade was a sale of €811k by Dhaliwal Harpreet S., published on 5 August 2026, equal to 0.011% of the market capitalisation.
Between a trade and the moment it shows up on SEC (Form 4), the median delay is 2 days. For comparison, the SEC allows two business days to file a Form 4. Sales are harder to read than purchases, since they often meet personal needs such as tax or diversification.
With 75 filings in twelve months, the company is more active than the median of 19 filings across the 5,811 companies we follow on the same exchange. Our records for Vaxcyte, Inc. go back to 2021, with no purchases and 76 sales on the open market in total. For the fiscal year to 31 December 2025, the annual 10-K puts net income at -766.6 m USD.
Other companies in the same sector with recent insider buying flagged by our signals: Cooper Companies, Inc. and Anixa Biosciences Inc. This summary is built from SEC (Form 4) disclosures alone and does not predict where the share price will go.
Analysts rate Vaxcyte, Inc. Strong Buy (bullish), based on 10 analysts. Average price target: US$117.30.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
FY ended December 2025 · cache
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Vaxcyte, Inc. is a clinical-stage biotechnology and vaccine company listed on the NASDAQ under ticker PCVX in the United States. Headquartered in San Carlos, California, the company was incorporated in 2013 under the name SutroVax and adopted the Vaxcyte name in 2020. For investors, it represents a specialized growth biotech with a science-led platform and no meaningful commercial product revenue yet, but with substantial optionality if its late-stage vaccine programs continue to advance successfully.
Vaxcyte’s business is built around its proprietary platform for designing and manufacturing high-fidelity proteins and antigens. The company’s technology originated from cell-free protein synthesis capabilities licensed from Sutro Biopharma and has been further developed internally to support the creation of next-generation vaccines. The strategic focus is on bacterial diseases, especially pneumococcal infections, where the company believes broader serotype coverage and stronger immune responses can create a better product profile than existing vaccines. Its lead asset is VAX-31, a next-generation pneumococcal conjugate vaccine candidate that management describes as the broadest-spectrum PCV in clinical development, with separate programs in adults and infants. VAX-24 has also been an important part of the company’s clinical validation work.
In competitive terms, Vaxcyte is trying to challenge established vaccine leaders in a market that is both medically important and commercially attractive. Pneumococcal vaccination is already a well-developed category, dominated by large pharmaceutical companies with approved products and global scale. Vaxcyte’s investment case therefore hinges on differentiation: wider serotype coverage, robust immunogenicity, and a potential best-in-class profile. The company does not yet have a broad commercial footprint; its geographic presence remains primarily U.S.-based, anchored by its California headquarters and an expanding domestic manufacturing strategy.
Recent developments have been especially important. In 2025 and 2026, Vaxcyte reported major clinical progress for VAX-31, including the initiation and enrollment of multiple Phase 3 adult trials and continued advancement of the infant program. The company also published positive clinical data in a respected medical journal, helping strengthen the scientific profile of its lead vaccine candidate. On the manufacturing side, Vaxcyte continued to invest in dedicated production capacity in the United States and in long-term manufacturing agreements, signaling that it is preparing for a potential future commercial launch. Overall, Vaxcyte remains a capital-intensive, high-risk, high-upside biotech story whose valuation will be driven primarily by clinical success, regulatory milestones, and manufacturing execution on the NASDAQ in the United States.
Purchases our model currently ranks for the recommendations list.
All recommendationsInsider filings
Over the last 90 days, 37 filings published between 27 July and 7 October 2026: 15 sales for EUR 2.5 million. 22 other filings (not open-market purchases or sales: grants, options, plans, sale notices, block transfers). Largest amounts: PICKERING GRANT (CHIEF EXECUTIVE OFFICER), sales of EUR 887,347; Dhaliwal Harpreet S. (Chief Technical Ops Officer), sales of EUR 810,891; GUGGENHIME ANDREW (PRESIDENT AND CFO), sales of EUR 467,208.
Summary written automatically from public filings, without human review. General information, identical for every reader: it is not investment advice or a recommendation to buy or sell. Investing involves a risk of capital loss. Generated on 13 October 2026 (UTC)
| Fiscal year end | Revenue | Net income | Diluted EPS | Dividend per share | Filing |
|---|---|---|---|---|---|
| Dec 2025 | n.d. | -766.6 m USD | -5.63 USD | 0.00 USD | 10-K |
| Dec 2024 | n.d. | -463.9 m USD | -3.80 USD | 0.00 USD | 10-K |
| Dec 2023 | n.d. | -402.3 m USD | -4.14 USD | 0.00 USD | 10-K |
| Dec 2022 | n.d. | -223.5 m USD | -3.44 USD | 0.00 USD | 10-K |
| Dec 2021 | n.d. | -100.1 m USD | -1.93 USD | 0.00 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.