1 insider bought €814k of shares over the last 90 days, the latest by Ciongoli Gregory Austin, filed 27 Aug 2026.
REGENXBIO Inc., classified in the Healthcare & Pharma sector, is a listed company. Its insiders report their share dealings to SEC (Form 4). 9 insiders have disclosed 28 filings since 22 October 2025.
The record shows 2 purchases on the open market worth €814k, made by 1 insider, against 2 sales worth €71k by 1 insider. Purchases outweigh sales by €742k. A purchase on the market is a deliberate choice to commit personal money, which is why it draws more attention than a grant. At €429k, the purchase published on 27 August 2026 by Ciongoli Gregory Austin is the largest of the period (0.10% of market cap). The buyers include 1 senior executive.
The latest purchase dates back some time: it was published 58 days ago, on 27 August 2026. The median gap between a trade and its publication by SEC (Form 4) is 2 days. For comparison, the SEC allows two business days to file a Form 4.
For context, the typical company on the same exchange (median of 3,171 companies) published 24 filings over the same period, against 28 filings here. Over the whole record (from 2016), the tally stands at 2 purchases and 434 sales. For the fiscal year to 31 December 2025, the annual 10-K puts revenue at 170.4 m USD and net income at -193.9 m USD.
This summary is built from SEC (Form 4) disclosures alone and does not predict where the share price will go.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate REGENXBIO Inc. Buy (bullish), based on 12 analysts. Average price target: US$23.58.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended December 2025 · cache
25 of 740 declarations
REGENXBIO Inc. is a U.S.-based biotechnology company listed on the Nasdaq market in the United States, focused on in vivo gene therapy. Headquartered in Rockville, Maryland, the company develops treatments intended to address severe genetic and degenerative diseases, with a particular emphasis on rare diseases and retinal disorders. Its core competitive asset is its proprietary NAV Technology platform, designed to support AAV-based gene delivery and durable therapeutic expression. Founded in 2009, REGENXBIO has evolved into a recognized gene-therapy developer through a mix of internal R&D and strategic pharmaceutical partnerships. ([ir.regenxbio.com](https://ir.regenxbio.com/?utm_source=openai))
The company’s pipeline is centered on several clinical and pre-commercial programs. The most advanced asset is RGX-202, a gene therapy candidate for Duchenne muscular dystrophy. In 2025 and 2026, REGENXBIO reported encouraging interim data, completed pivotal enrollment, and began commercial production activities, with top-line pivotal data expected in early Q2 2026 and a BLA filing targeted for mid-2026. In rare lysosomal diseases, the company is developing RGX-121 for MPS II and RGX-111 for MPS I through a partnership with Nippon Shinyaku. In ophthalmology, REGENXBIO is advancing ABBV-RGX-314 with AbbVie for wet AMD and diabetic retinopathy. ([ir.regenxbio.com](https://ir.regenxbio.com/news-releases/news-release-details/regenxbio-announces-completion-pivotal-enrollment-and-initiates/?utm_source=openai))
From a commercial perspective, REGENXBIO is still largely a development-stage company, but its risk-reward profile has improved as its lead programs move closer to potential approval. Its competitive positioning is built on a combination of proprietary platform know-how, integrated manufacturing capabilities, and a pipeline aimed at high-unmet-need indications. The company manufactures RGX-202 at its Manufacturing Innovation Center in Rockville, which strengthens supply-chain control and could support future launch readiness. ([ir.regenxbio.com](https://ir.regenxbio.com/news-releases/news-release-details/regenxbio-announces-completion-pivotal-enrollment-and-initiates/?utm_source=openai))
Geographically, REGENXBIO remains primarily U.S.-anchored, with headquarters, research, and manufacturing operations in the United States, while its partnerships broaden potential commercialization into international markets. Agreements with AbbVie and Nippon Shinyaku extend the company’s reach and validate its technology platform. Recent highlights include continued positive data for RGX-202, ongoing regulatory progress for RGX-121, and manufacturing scale-up tied to a possible mid-2026 launch path. For European investors, this is a high-upside biotech name, but one that remains highly dependent on clinical execution, regulatory decisions, and eventual market adoption. ([ir.regenxbio.com](https://ir.regenxbio.com/news-releases/news-release-details/regenxbio-reports-new-positive-interim-data-phase-iii-affinity/?utm_source=openai))
| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 170.4 m USD | -193.9 m USD | -3.76 USD | 10-K |
| Dec 2024 | 83.3 m USD | -227.1 m USD | -4.59 USD | 10-K |
| Dec 2023 | 90.2 m USD | -263.5 m USD | -6.02 USD | 10-K |
| Dec 2022 | 112.7 m USD | -280.3 m USD | -6.50 USD | 10-K |
| Dec 2021 | 470.3 m USD | 127.8 m USD | 2.91 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.