No insider purchase over the last 90 days. The latest, by ALEXANDER MARGARET A., was filed 29 Jan 2025.
This page follows insider dealings at Ovid Therapeutics Inc. as filed with SEC (Form 4), a company from the Healthcare & Pharma sector. In the past year (22 October 2025 to 22 October 2026), 12 filings came from 9 insiders.
Only sales appear on the open market, 2 sales in all totalling €25k, filed by 2 insiders. One trade stands out by size: a sale of €14k from Alexander Margaret A., disclosed on 2 March 2026.
Typically, a trade is published a median of 2 days after it takes place. Section 16 rules allow two business days to file each Form 4. Sales are harder to read than purchases, since they often meet personal needs such as tax or diversification.
With 12 filings in twelve months, the company is quieter than the median of 24 filings across the 3,171 companies we follow on the same exchange. Over the whole record (from 2017), the tally stands at 10 purchases and 6 sales. For the fiscal year to 31 December 2025, the annual 10-K puts revenue at 7.3 m USD and net income at -17.4 m USD.
Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate Ovid Therapeutics Inc. Strong Buy (bullish), based on 10 analysts. Average price target: US$6.00.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
FY ended December 2025 · cache
25 of 40 declarations
Ovid Therapeutics Inc. (NASDAQ: OVID) is a United States-based biopharmaceutical company listed on the NASDAQ market and headquartered in New York, United States. Founded in 2014 and operational since that year, Ovid focuses on small-molecule medicines for brain disorders, particularly conditions driven by neuronal hyperexcitability and impaired excitatory/inhibitory balance. The company is best understood as a clinical-stage neuroscience biotech: it has no broad commercial product base, and its valuation is primarily driven by pipeline execution, clinical readouts, regulatory progress, and financing discipline.
Ovid’s current strategy is centered on a differentiated neuroscience platform. Its lead development program, OV329, is a next-generation GABA-aminotransferase inhibitor being developed primarily for drug-resistant epilepsies and related seizure disorders. Management has reported encouraging early clinical data, including favorable safety, tolerability, pharmacokinetic, and pharmacodynamic findings, supporting advancement into later-stage studies. The company has also expanded OV329 into additional seizure-related indications, including tuberous sclerosis complex seizures and infantile spasms, which broadens the commercial opportunity while keeping the development theme focused on high unmet need.
A second strategic pillar is the KCC2 portfolio. Ovid is advancing OV4071, an oral direct activator of the KCC2 transporter, as a potential first-in-class approach aimed at restoring inhibitory tone in the brain. The company’s KCC2 thesis is mechanistic and differentiated: rather than simply treating symptoms, it seeks to address a core biological control point in disorders where hyperexcitability and circuit dysfunction are central. Ovid also used OV350, an intravenous KCC2 direct activator, as a human proof-of-concept and target-validation program, providing clinical support for the broader KCC2 franchise.
Competitively, Ovid operates in a crowded but scientifically attractive field that includes larger pharmaceutical companies and specialist neuroscience biotechs. Its relative strengths lie in target differentiation, a focused pipeline, and the potential to build a proprietary franchise around epilepsy, psychosis, and other CNS disorders. Its limitations are those typical of small-cap biotech: dependence on clinical success, regulatory approvals, and access to capital. As such, the stock carries meaningful event risk, but also meaningful upside if proof-of-concept data continue to confirm the platform.
Recent milestones have been important. In 2026, Ovid reported continued pipeline progress, including Phase 1 dosing for OV4071, expansion of OV329 into complementary seizure indications, and new financing that strengthened its runway. The company has also indicated a longer cash runway and multiple anticipated clinical catalysts over the next 18 to 24 months. For investors following U.S. healthcare equities, OVID on NASDAQ offers a focused, high-risk/high-reward exposure to CNS innovation in the United States.
| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 7.3 m USD | -17.4 m USD | n.d. | 10-K |
| Dec 2024 | 566,000 USD | -26.4 m USD | n.d. | 10-K |
| Dec 2023 | 392,000 USD | -52.3 m USD | -0.74 USD | 10-K |
| Dec 2022 | 1.5 m USD | -54.2 m USD | -0.77 USD | 10-K |
| Dec 2021 | 208.4 m USD | 122.8 m USD | 1.76 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.