No insider purchase over the last 90 days. The latest was filed 13 May 2025.
This page follows insider dealings at Jazz Pharmaceuticals plc as filed with SEC (Form 4), a company from the Healthcare & Pharma sector based in Ireland, Ireland. The group dates from 2003. Over the twelve months to 18 October 2026, 95 filings were filed, from 37 insiders.
All open-market trades in the period are sales: 23 sales worth €26.8M, by 7 insiders, with no purchase on record. The largest single trade was a sale of €4.2M by Iannone Robert, published on 31 August 2026, equal to 0.031% of the market capitalisation.
Between a trade and the moment it shows up on SEC (Form 4), the median delay is 4 days. Section 16 rules allow two business days to file each Form 4. A sale on its own says little: insiders also sell to pay tax, fund a purchase or diversify.
Across the 5,458 companies tracked on its exchange, the median is 22 filings; at 95 filings, this issuer sits above that mark. Looking back to 2016, when coverage begins, insiders filed 1 purchase and 114 sales. The 10-K for the year ended 31 December 2025 shows 4.27 bn USD of revenue and -356.1 m USD of net income.
Other companies in the same sector with recent insider buying flagged by our signals: Anixa Biosciences Inc and Vivos Inc. This summary is built from SEC (Form 4) disclosures alone and does not predict where the share price will go.
+2 other insiders
Analysts rate Jazz Pharmaceuticals plc Buy (bullish), based on 21 analysts. Average price target: US$292.81.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended December 2025 · cache
25 of 355 declarations
Jazz Pharmaceuticals plc is a specialty biopharmaceutical company listed on the Nasdaq market in the United States under the ticker JAZZ. For international investors, the company stands out for a focused portfolio built around high-value medicines in sleep disorders, rare epilepsy, and oncology. Founded in 2003, Jazz expanded through a series of acquisitions and strategic integrations, including the merger with Azur Pharma, which helped establish Dublin as its global headquarters. Even so, the company maintains a significant operational presence in the United States, and its revenue base remains heavily linked to the U.S. market.
Jazz’s business model is anchored by several key commercial franchises. In sleep medicine, Xywav is one of the company’s flagship products, aimed at rare sleep disorders and differentiated by a lower-sodium oxybate formulation versus legacy products. In epilepsy, Epidiolex is a core asset in rare seizure syndromes. In oncology, Jazz markets Zepzelca in certain lung cancer settings, Rylaze/Enrylaze in hematology-related indications, and newer franchises such as Modeyso and Ziihera. This mix gives the company a broader therapeutic footprint, although it remains concentrated in specialized, highly regulated niche markets.
From a competitive standpoint, Jazz occupies a solid mid-tier position in rare disease and niche oncology. Its strengths include deep clinical expertise, high regulatory barriers, targeted commercial capabilities, and a lifecycle-management approach to its products. At the same time, the company faces meaningful competition from large pharmaceutical groups, generics and biosimilars, and, in some cases, newer treatment alternatives. As with most specialty pharma names, the investment case also carries typical sector risks: regulatory approvals, pricing pressure, litigation exposure, and execution risk around new launches.
Geographically, Jazz operates across North America, Europe, and Australia, and it is expanding into Japan while also using partnerships to reach other regions. Recent company milestones underscore a constructive pipeline trajectory: in 2025, Jazz reported FDA accelerated approval for Modeyso, positive phase 3 data for Zepzelca combined with atezolizumab in extensive-stage small cell lung cancer, and major progress for Ziihera in HER2-positive gastroesophageal cancers. Financial updates through 2025 and into early 2026 highlighted continued growth in the Xywav, Epidiolex, and Zepzelca franchises, supporting the company’s growth profile.
In short, Jazz Pharmaceuticals plc is a specialty healthcare name listed on the Nasdaq in the United States, combining an established commercial base with clinical pipeline optionality and regulatory catalysts, while remaining highly sensitive to FDA decisions and launch execution.
Purchases our model currently ranks for the recommendations list.
All recommendationsInsider filings
Over the last 90 days, 45 filings published between 3 August and 7 October 2026: 11 sales for EUR 20.1 million. 34 other filings (not open-market purchases or sales: grants, options, plans, sale notices, block transfers). Largest amounts: Iannone Robert (EVP, Global Head of R&D & CMO), sales of EUR 16.5 million; COZADD BRUCE C (Director), sales of EUR 2.5 million; GALA RENEE D (President & CEO), sales of EUR 838,846.
Summary written automatically from public filings, without human review. General information, identical for every reader: it is not investment advice or a recommendation to buy or sell. Investing involves a risk of capital loss. Generated on 13 October 2026 (UTC)
Headquarters: Ireland, Ireland · Founded: 2003 · Wikipedia article
Source: Wikidata (CC0).
| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 4.27 bn USD | -356.1 m USD | -5.84 USD | 10-K |
| Dec 2024 | 4.07 bn USD | 560.1 m USD | 8.65 USD | 10-K |
| Dec 2023 | 3.83 bn USD | 414.8 m USD | 6.10 USD | 10-K |
| Dec 2022 | 3.66 bn USD | -224.1 m USD | -3.58 USD | 10-K |
| Dec 2021 | 3.09 bn USD | -329.7 m USD | -5.52 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.