BioXcel Therapeutics, Inc. belongs to the Healthcare & Pharma sector. Filings by its managers are published through SEC (Form 4). The last twelve months, up to 18 October 2026, brought 21 filings signed by 5 insiders.
No insider bought on the market over the period, while 4 insiders filed 4 sales totalling €37k. Mehta Vimal filed the largest sale, €18k, on 22 May 2026, which represents 0.059% of the company's market value.
Across the 5,808 companies tracked on its exchange, the median is 19 filings; at 21 filings, this issuer sits above that mark. Since 2021, the database holds no purchases and 8 sales by insiders of the company. On the fundamentals side, the SEC filing (10-K) for the period ending 31 December 2025 lists revenue at 642,000 USD and net income at -69.9 m USD.
Filings reach the SEC (Form 4) feed a median of 2 days after the trade. Section 16 rules allow two business days to file each Form 4. Sales are harder to read than purchases, since they often meet personal needs such as tax or diversification.
In the same sector, recent insider purchases at Cooper Companies, Inc. and Cytosorbents Corp also feature in our signals. Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
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BioXcel Therapeutics, Inc. is a U.S.-listed biopharmaceutical company trading on the NASDAQ under the ticker BTAI. Headquartered in New Haven, Connecticut, United States, the company was incorporated in 2017 and was built around a differentiated strategy: using artificial intelligence and data-driven methods to accelerate drug discovery and development, especially in neuroscience. For French-speaking investors in France, Belgium, and Switzerland, BioXcel fits the profile of a high-risk, high-upside biotech story, where valuation is driven less by current sales and more by clinical execution, regulatory milestones, and the optionality of future label expansions.
The company’s lead and most advanced asset is BXCL501, commercialized as IGALMI®, a sublingual dexmedetomidine film approved in the United States for the acute treatment of agitation associated with schizophrenia or bipolar I or II disorder in adults. FDA approval in 2022 established BioXcel’s first commercial product and validated the company’s neuroscience-focused platform. Since then, management has pursued additional development paths, including a supplemental NDA aimed at expanding IGALMI into the at-home or outpatient setting. BioXcel is also advancing late-stage clinical programs for BXCL501 in agitation associated with Alzheimer’s dementia and related neuropsychiatric settings.
BioXcel’s history is tied to BioXcel LLC and a broader AI-enabled drug-development concept that combined machine learning with clinical and translational expertise. Over time, the company narrowed its focus toward the most promising neuroscience programs, particularly BXCL501, while keeping a relatively lean operating structure. That strategic refocus has also translated into a strong emphasis on liquidity management, cost discipline, and governance refreshes, reflecting the capital-intensive nature of biotech development.
From a competitive standpoint, BioXcel operates in a market with substantial unmet need. Acute agitation in schizophrenia, bipolar disorder, and dementia is clinically significant, yet treatment options remain limited and often based on older standards of care. BioXcel’s differentiation lies in its formulation, intended onset profile, and potential use across settings, including institutional and potentially at-home care. That said, it competes not only with existing therapies used in practice, but also with the possibility of new entrants if the category expands. Its geographic footprint is mainly U.S.-focused, with headquarters and core operations in the United States.
Recent company highlights include FDA acceptance of a supplemental NDA for IGALMI in the at-home setting, ongoing progress in the SERENITY and TRANQUILITY trials, and a steady stream of SEC filings including Form 4 insider transaction reports. These developments underscore a company that is still largely in execution mode: BioXcel is trying to convert one approved product into a broader franchise while preserving enough financial flexibility to support its pipeline. For equity investors, BTAI remains a speculative healthcare name with meaningful binary catalysts and a valuation highly sensitive to clinical and regulatory outcomes.
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All recommendations| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 642,000 USD | -69.9 m USD | -5.73 USD | 10-K |
| Dec 2024 | 2.3 m USD | -59.6 m USD | -23.51 USD | 10-K |
| Dec 2023 | 1.4 m USD | -179.1 m USD | -98.33 USD | 10-K |
| Dec 2022 | 375,000 USD | -165.8 m USD | -5.92 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.