No insider purchase over the last 90 days. The latest was filed 29 Jun 2021.
Aravive, Inc., classified in the Healthcare & Pharma sector, is a listed company. Its insiders report their share dealings to SEC (Form 4). Nothing new has been filed by managers of Aravive, Inc. in twelve months, the latest record being from 26 October 2022.
Our records for Aravive, Inc. go back to 2016, with 2 purchases and 2 sales on the open market in total.
Elsewhere in the same sector, our signals recently picked up insider purchases at Anixa Biosciences Inc and Vivos Inc. Source: insider filings from SEC (Form 4). Past trades are no guide to future returns.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
FY ended December 2022 · cache
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Aravive, Inc. is a U.S.-based biopharmaceutical company that was focused on oncology and, more broadly, the development of therapies intended to slow the progression of severe diseases. The company was incorporated in 2008 in Delaware and had its headquarters and principal operations in Houston, Texas, United States. Its shares traded on the Nasdaq market under the ticker ARAV. In January 2024, Aravive announced plans to delist from Nasdaq and to suspend its public reporting obligations in connection with an asset transfer for the benefit of creditors and a planned liquidation. For investors, that context is crucial: Aravive should be viewed as a restructuring/special-situation name rather than a conventional operating growth stock.
From a business-model standpoint, Aravive was a clinical-stage company with no established commercial product base. Its value proposition was built around research and development, with the company seeking to advance a lead candidate, AVB-500. AVB-500 is an ultra-high-affinity decoy protein designed to intercept the GAS6-AXL signaling pathway. That pathway has been studied in cancer biology because of its potential links to tumor growth, cell survival, metastasis, and treatment resistance. In practical terms, Aravive’s core activity was drug discovery and clinical validation, not manufacturing or the sale of approved therapies.
The company’s market position was therefore that of a small, highly specialized biotechnology developer operating in one of the most competitive areas of healthcare innovation. Aravive competed indirectly with much larger oncology franchises at diversified pharmaceutical companies, as well as with numerous venture-backed biotech peers pursuing targeted cancer mechanisms. Its differentiation came from the scientific rationale of the GAS6-AXL target and the specificity of its decoy-protein approach. However, the downside was equally clear: extreme dependence on capital markets, high research spending, binary clinical risk, and limited diversification. Those are typical characteristics of early-stage biotech, but they became especially important as Aravive’s financial and listing situation deteriorated.
Historically, the company’s profile was one of a single-lead-asset biotech, meaning investor attention was concentrated on pipeline progress, trial readouts, financing events, and strategic alternatives. Its geographic footprint was centered in the United States, with Houston as the main corporate base. The most important recent development was not a product launch or a regulatory approval, but the company’s move toward delisting and liquidation in 2024. That makes Aravive a name primarily relevant for event-driven investors and analysts following distressed healthcare situations, rather than for long-term fundamental growth investors.
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