No insider purchase over the last 90 days. The latest was filed 03 Nov 2021.
Headquartered in Cranbury, United States, Amicus Therapeutics, Inc. belongs to the Healthcare & Pharma sector and traces its origins to 2002. Filings by its managers are published through SEC (Form 4). Over the twelve months to 18 October 2026, 37 filings were filed, from 14 insiders.
There is no open-market purchase to report; the filings show 5 sales worth €1.3M by 2 insiders. Biggest ticket of the year: €310k, sold by Clark David Michael and made public on 23 December 2025.
Filings reach the SEC (Form 4) feed a median of 3 days after the trade. The legal deadline for a Form 4 is two business days after the transaction. A sale on its own says little: insiders also sell to pay tax, fund a purchase or diversify.
For context, the typical company on the same exchange (median of 5,813 companies) published 19 filings over the same period, against 37 filings here. Over the whole record (from 2016), the tally stands at 8 purchases and 82 sales. For the fiscal year to 31 December 2025, the annual 10-K puts revenue at 634.2 m USD and net income at -27.1 m USD.
Elsewhere in the same sector, our signals recently picked up insider purchases at Cooper Companies, Inc. and Anixa Biosciences Inc. This summary is built from SEC (Form 4) disclosures alone and does not predict where the share price will go.
Entry is the close on the day after publication, the first price a reader could act on. Prices in the listing currency. Past moves are not a forecast.
Analysts rate Amicus Therapeutics, Inc. Hold (neutral), based on 5 analysts. Average price target: US$14.50.
This score ranks the purchase within its own market. A position size is suggested only on the venues of the backtested strategy universe; elsewhere, signals stay on watch. Not investment advice.
Transparent value + quality ranking, distinct from the insider signal.
FY ended December 2025 · cache
25 of 320 declarations
Amicus Therapeutics, Inc. (ticker: FOLD) is a U.S.-based biopharmaceutical company listed on the NASDAQ market in the United States. Headquartered in Princeton, New Jersey, the company is focused on rare diseases and has built its strategy around precision medicine, commercial execution, and a growing late-stage/approved product portfolio. Founded in the early 2000s, Amicus has evolved from a development-stage biotech into a global rare-disease company with meaningful commercial revenues and a clear ambition to become a leading player in the lysosomal and inherited metabolic disease space.
The company’s business is currently anchored by two core franchises. The first is Galafold (migalastat), an oral precision medicine used in certain adults with Fabry disease who carry amenable GLA variants. Galafold remains the primary revenue engine and has established a broad international footprint, supported by patient growth, physician adoption, and ongoing commercial expansion. The second franchise is Pombiliti + Opfolda (cipaglucosidase alfa plus miglustat), a treatment for late-onset Pompe disease that has been rolled out across multiple geographies following regulatory approvals. Beyond these marketed assets, Amicus continues to advance clinical and scientific programs intended to broaden labels and strengthen its long-term rare-disease franchise, although the equity story is still heavily driven by the two commercial products.
From a competitive perspective, Amicus occupies a differentiated niche in lysosomal storage disorders. Its positioning is built on oral therapy where possible, disease-specific expertise, and a global commercial infrastructure tailored to rare-disease markets. This allows the company to compete with larger and better-capitalized pharmaceutical groups while preserving a specialized profile that can be attractive in orphan-drug categories. The company sells products in the United States and internationally, with a presence across Europe, North America, Australia, and parts of Asia.
Recent highlights matter for investors. In 2025, Amicus announced the approval of Pombiliti + Opfolda in Japan, extending its international reach in Pompe disease. The company also reported strong 2024 revenue growth, driven by continued Galafold demand and the first full year of commercial launch for Pombiliti + Opfolda, while signaling a path toward further growth and improving profitability. For French-, Belgian-, and Swiss-based investors, FOLD is therefore a rare-disease growth story combining commercial expansion, regulatory catalysts, and geographic diversification, with the usual biotech risks around reimbursement, execution, and competitive pressure.
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All recommendationsHeadquarters: Cranbury, United States · Founded: 2002 · Wikipedia article
Source: Wikidata (CC0).
| Fiscal year end | Revenue | Net income | Diluted EPS | Filing |
|---|---|---|---|---|
| Dec 2025 | 634.2 m USD | -27.1 m USD | -0.09 USD | 10-K |
| Dec 2024 | 528.3 m USD | -56.1 m USD | -0.18 USD | 10-K |
| Dec 2023 | 399.4 m USD | -151.6 m USD | -0.51 USD | 10-K |
| Dec 2022 | 329.2 m USD | -236.6 m USD | -0.82 USD | 10-K |
| Dec 2021 | 305.5 m USD | -250.5 m USD | -0.92 USD | 10-K |
Amounts in USD, as filed (forms 10-K, 20-F or 40-F). Source: SEC EDGAR.